(Radio)active Neurogenesis in the Human Hippocampus

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(Radio)active Neurogenesis in the Human Hippocampus Mazen A. Kheirbek, René Hen Cell Volume 153, Issue 6, Pages 1183-1184 (June 2013) DOI: 10.1016/j.cell.2013.05.033 Copyright © 2013 Elsevier Inc. Terms and Conditions

Figure 1 Comparative Rates of Adult Neurogenesis in Mice and Men In contrast to the very low levels of adult neurogenesis reported in the human olfactory bulb (blue line), the human hippocampus continues to generate neurons at a steady rate well into old age with only a modest decline throughout adulthood (red line). The rate of neurogenesis in adult humans is comparable to levels seen in middle-aged rodents (9 months old; intersection of green line and red line). These results suggest that studies in rodents revealing the role of adult hippocampal neurogenesis in cognitive function (pattern separation) and emotional behavior (mood/anxiety) may also hold true in adult humans. Cell 2013 153, 1183-1184DOI: (10.1016/j.cell.2013.05.033) Copyright © 2013 Elsevier Inc. Terms and Conditions