Cliques and Schisms of Cancer Genes

Slides:



Advertisements
Similar presentations
Waging War on Cancer with the Sword of Immunity Cell Volume 158, Issue 2, (July 2014) DOI: /j.cell Copyright © 2014 Terms and Conditions.
Advertisements

A Role for Dystroglycan in Basement Membrane Assembly Michael D Henry, Kevin P Campbell Cell Volume 95, Issue 6, Pages (December 1998) DOI: /S (00)
Lessons from Hereditary Colorectal Cancer
Wood Formation in Trees Is Increased by Manipulating PXY-Regulated Cell Division J. Peter Etchells, Laxmi S. Mishra, Manoj Kumar, Liam Campbell, Simon.
Origins of Metastatic Traits Sakari Vanharanta, Joan Massagué Cancer Cell Volume 24, Issue 4, Pages (October 2013) DOI: /j.ccr
Making Proteins in the Powerhouse B. Martin Hällberg, Nils-Göran Larsson Cell Metabolism Volume 20, Issue 2, Pages (August 2014) DOI: /j.cmet
Control of Gene Expression
Xenobiotics Shape the Physiology and Gene Expression of the Active Human Gut Microbiome Corinne Ferrier Maurice, Henry Joseph Haiser, Peter James Turnbaugh.
Cancer Metabolism Cell Volume 148, Issue 3, (February 2012) DOI: /j.cell Copyright © 2012 Terms and Conditions Terms and Conditions.
Ancient Endo-siRNA Pathways Reveal New Tricks Julie M. Claycomb Current Biology Volume 24, Issue 15, Pages R703-R715 (August 2014) DOI: /j.cub
Evolution of the Cancer Stem Cell Model Antonija Kreso, John E. Dick Cell Stem Cell Volume 14, Issue 3, Pages (March 2014) DOI: /j.stem
The Landscape of Microsatellite Instability in Colorectal and Endometrial Cancer Genomes Tae-Min Kim, Peter W. Laird, Peter J. Park Cell Volume 155, Issue.
The Good Fat Cell Volume 147, Issue 7, (December 2011) DOI: /j.cell Copyright © 2011 Terms and Conditions Terms and Conditions.
Healthy clocks, healthy body, healthy mind Akhilesh B. Reddy, John S. O’Neill Trends in Cell Biology Volume 20, Issue 1, Pages (January 2010) DOI:
MiR-137 Modulates a Tumor Suppressor Network-Inducing Senescence in Pancreatic Cancer Cells Mathieu Neault, Frédérick A. Mallette, Stéphane Richard Cell.
Hedgehog Signaling Restrains Bladder Cancer Progression by Eliciting Stromal Production of Urothelial Differentiation Factors Kunyoo Shin, Agnes Lim, Chen.
Shaping Genetic Alterations in Human Cancer: The p53 Mutation Paradigm Thierry Soussi, Klas G. Wiman Cancer Cell Volume 12, Issue 4, Pages (October.
Liver Cancer Checks in When Bile Acid Clocks Out
A Novel Link between Inflammation and Cancer
Cancer: Inappropriate Expression of Stem Cell Programs?
Man's Best Friend: Utilizing Naturally Occurring Tumors in Dogs to Improve Chimeric Antigen Receptor T-cell Therapy for Human Cancers  Melinda Mata, Stephen.
We Contain Multitudes: The Protean Face of Retinoblastoma
Kristin G. Anderson, Ingunn M. Stromnes, Philip D. Greenberg 
Settling a Nervous Stomach: The Neural Regulation of Enteric Cancer
Scratching the Surface of Immunotherapeutic Targets in Neuroblastoma
Intravascular Survival and Extravasation of Tumor Cells
Kenneth L. Scott, Scott Powers  Cancer Cell 
Metastasis gets site specific
Christian Grommes, Anas Younes  Cancer Cell 
Michael W.M. Kühn, Scott A. Armstrong  Cancer Cell 
Scratching the Surface of Immunotherapeutic Targets in Neuroblastoma
Michael W.M. Kühn, Scott A. Armstrong  Cancer Cell 
DAISY: Picking Synthetic Lethals from Cancer Genomes
Tipping the Balancing ACT
The Lethal Clone in Prostate Cancer: Redefining the Index
Does CSF1R Blockade Turn into Friendly Fire?
IDH1, Histone Methylation, and So Forth
Doria Filipponi, Julius Muller, Alexander Emelyanov, Dmitry V. Bulavin 
Pontine Infantile Glioma Simplified
Laurence Zitvogel, Guido Kroemer  Cancer Cell 
Gastroenterology news
New Views into the Genetic Landscape of Metastatic Breast Cancer
In This Issue Cell Volume 158, Issue 5, (August 2014)
MicroRNAs and Parallel Stem Cell Lives
Choose and Use Your Chemical Probe Wisely to Explore Cancer Biology
Volume 20, Issue 8, Pages v-vi (August 2012)
Training for the infectious diseases speciality in Norway
Volume 152, Issue 1, (January 2013)
Mismatch Repair-Deficient Cancers Are Targets for Anti-PD-1 Therapy
Volume 130, Issue 6, (September 2007)
Interactions between cytomegalovirus and the p53 tumor suppressor gene in atherosclerotic vascular disease  Inge O. Baas, G. Johan A. Offerhaus, Ralph.
Volume 31, Issue 2, Pages (February 2017)
847. Eradication of Therapy-Resistant Human Prostate Tumors Using an Ultrasound Guided Site-Specific Cancer Terminator Virus Delivery Approach    Molecular.
Kenneth L. Scott, Scott Powers  Cancer Cell 
Volume 143, Issue 6, (December 2010)
Volume 26, Issue 4, Pages (April 2018)
Table of Contents Nurse Leader Volume 16, Issue 4, (August 2018)
Volume 14, Issue 4, Pages (October 2008)
Stage I Non-small Cell Lung Cancer: Results for Surgery in a Patterns-of-Care Study in Sydney and for High-Dose Concurrent End-Phase Boost Accelerated.
Volume 70, Issue 3, Pages (August 2006)
Splicing and Dicing MYC-Mediated Synthetic Lethality
Will Bailis, Justin A. Shyer, Michael Chiorazzi, Richard A. Flavell 
To Infinium, and Beyond! Cancer Cell
Volume 163, Issue 4, (November 2015)
Nicholas McGranahan, Charles Swanton  Cancer Cell 
Volume 163, Issue 2, (October 2015)
Volume 134, Issue 6, (September 2008)
In This Issue Cell Volume 145, Issue 3, (April 2011)
Volume 148, Issue 1, (January 2012)
624. Randomized Phase II Trial of Adjuvant Autologous Tumor Cell Vaccine (FANG™) for High Risk Stage III/IV Ovarian Cancer: Preliminary Results    Molecular.
Presentation transcript:

Cliques and Schisms of Cancer Genes Peter J. Campbell  Cancer Cell  Volume 32, Issue 2, Pages 129-130 (August 2017) DOI: 10.1016/j.ccell.2017.07.009 Copyright © 2017 Terms and Conditions

Figure 1 Patterns of Pairwise Gene Associations Within a given tumor, two genes can be randomly assorted, occur together more often than expected by chance (co-occurrence), or very rarely occur together in the same clone (mutual exclusivity). These patterns have different biological implications. Cancer Cell 2017 32, 129-130DOI: (10.1016/j.ccell.2017.07.009) Copyright © 2017 Terms and Conditions