VUMC Core Managers Meeting VUMC Office of Research May 10, 2018

Agenda Vanderbilt Environmental Health & Safety Presentation SEASR 2018 Conference SOM Shared Resource & Core Retreat Rigor & Reproducibility Q&A

Vanderbilt Environmental Health & Safety Robin Trundy

SEASR 2018 Conference June 27-29 Emory Conference Center Hotel Atlanta, GA “Scientific Rigor and Reproducibility” MEETING AND HOTEL REGISTRATION IS NOW OPEN How to write SOPs For full agenda, registration, and hotel reservations visit: seasr.abrf.org Analysis and storage of “Big Data” Quality systems primer Networking and more! “Omics” research best practices Study design considerations Lisa McShane, PhD National Institutes of Health Tim Errington, PhD Center for Open Science Kevin Knudtson, PhD University of Iowa

Application deadline: May 28, 2018 SEASR Executive Board (EB) is looking for 4 motivated core directors, administrators, managers, or staff to serve on the SEASR EB from 2018-2022. The four members will serve in the capacity of Registration Coordinator, Secretary, Sponsor Coordinator-elect, or Treasurer-elect during the first year on the EB Application deadline: May 28, 2018 Questions? Contact Kim.Dahlman@Vanderbilt.edu

Core Retreat Save the date… Shared resource & School of medicine Sessions include: Strategic planning Professional development Marketing Metrics of Success SOP writing School of medicine Shared resource & Core Retreat When: September 12, 2018 Where: Scarritt Bennett Center Who: All SOM Core managers, directors, & staff

NIH Initiative for Rigor and Reproducibility https://www.nih.gov/research-training/rigor-reproducibility/principles-guidelines-reporting-preclinical-research

NIH Initiative for Rigor and Reproducibility Begun in 2016 Focus on four areas deemed important for enhancing rigor and transparency: The scientific premise forming the basis of the proposed research Rigorous experimental design for robust and unbiased results Consideration of relevant biological variables  Authentication of key biological and/or chemical resources  https://grants.nih.gov/grants/guide/notice-files/NOT-OD-16-011.html

NIH Initiative for Rigor and Reproducibility Important role for research cores Facilitate good experimental design when applicable Develop and implement well-defined SOPs, QC/QA practices for core services Offer and promote authentication services for key biological and/or chemical resources to help achieve compliance with the NIH guidelines cell line authentication antibody validation chemical reagent testing/optimization

NIH Initiative for Rigor and Reproducibility Important role for research cores New opportunity: Office of Research working group to consider best practices for rigor and reproducibility in VUMC cores Goal: Develop guidance and principles applicable to all VUMC cores to encourage increased rigor and reproducibility Interested? Contact s.meyn@vumc.org

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Questions?