Predictors of survival in adults undergoing extracorporeal membrane oxygenation with severe infections Aristine Cheng, MD, Hsin-Yun Sun, MD, Mao-Song.

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Predictors of survival in adults undergoing extracorporeal membrane oxygenation with severe infections Aristine Cheng, MD, Hsin-Yun Sun, MD, Mao-Song Tsai, MD, Wen-Je Ko, MD, Pi-Ru Tsai, BSc, Fu-Chang Hu, ScD, Yee-Chun Chen, MD, PhD, Shan-Chwen Chang, MD, PhD The Journal of Thoracic and Cardiovascular Surgery Volume 152, Issue 6, Pages 1526-1536.e1 (December 2016) DOI: 10.1016/j.jtcvs.2016.08.038 Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

Figure 1 Flow diagram of patient selection. ECMO, Extracorporeal membrane oxygenation; NTUH, National Taiwan University Hospital. The Journal of Thoracic and Cardiovascular Surgery 2016 152, 1526-1536.e1DOI: (10.1016/j.jtcvs.2016.08.038) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

Figure 2 The types of life-threatening infections in 151 septic adults receiving extracorporeal life support between 2001 and 2011 classified by primary site of infection and mode of extracorporeal life support. VA, Venoarterial; ECMO, extracorporeal membrane oxygenation; VV, venovenous; RTI, respiratory tract infection; BSI, primary bloodstream infection; IAI, intra-abdominal infection; IE, infective endocarditis; MD, mediastinitis; NF, necrotizing fasciitis; UTI, bacteremic urinary tract infection; MY, myocarditis. The Journal of Thoracic and Cardiovascular Surgery 2016 152, 1526-1536.e1DOI: (10.1016/j.jtcvs.2016.08.038) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

Figure 3 Kaplan-Meier estimate of the survival curves for early rescue (admission-to-ECMO onset within 96 hours) versus secondary or late rescue (admission-to-ECMO interval after the initial 96 hours of hospitalization). A, For the entire cohort of 151 septic adults. B, For the well-selected cohort aged 75 years or younger without end-stage comorbidities. ECMO, Extracorporeal membrane oxygenation. The Journal of Thoracic and Cardiovascular Surgery 2016 152, 1526-1536.e1DOI: (10.1016/j.jtcvs.2016.08.038) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

Early (within first 96 hours of admission) versus late rescue impacts survival on extracorporeal membrane oxygenation. The Journal of Thoracic and Cardiovascular Surgery 2016 152, 1526-1536.e1DOI: (10.1016/j.jtcvs.2016.08.038) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

Video 1 Emergent set-up of a venoarterial extracorporeal membrane oxygenation circuit via the femoral route in an elderly patient with massive pulmonary embolism requiring continuous cardiopulmonary resuscitation to bridge to open thrombectomy. Video available at: http://www.jtcvsonline.org/article/S0022-5223(16)31068-6/addons. The Journal of Thoracic and Cardiovascular Surgery 2016 152, 1526-1536.e1DOI: (10.1016/j.jtcvs.2016.08.038) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions