Cryopreservation of ovarian tissue for fertility preservation: no evidence of malignant cell contamination in ovarian tissue from patients with breast.

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Cryopreservation of ovarian tissue for fertility preservation: no evidence of malignant cell contamination in ovarian tissue from patients with breast cancer Mikkel Rosendahl, M.D., Ph.D., Vera Timmermans Wielenga, M.D., D.M.Sc., Lotte Nedergaard, M.D., D.M.Sc., Stine Gry Kristensen, M.Sc., Erik Ernst, M.D., Ph.D., Per Emil Rasmussen, M.D., Michael Anderson, M.D., D.M.Sc., Kirsten Tryde Schmidt, M.D., Ph.D., Claus Yding Andersen, M.Sc., D.M.Sc. Fertility and Sterility Volume 95, Issue 6, Pages 2158-2161 (May 2011) DOI: 10.1016/j.fertnstert.2010.12.019 Copyright © 2011 American Society for Reproductive Medicine Terms and Conditions

Figure 1 Ovarian cortex from one of the 51 women with breast cancer. Histologic and immunohistochemical analysis shows no signs of metastatic infiltration. (A) H&E. (B) WT-1. (C) CK-7. Magnification, ×10. Fertility and Sterility 2011 95, 2158-2161DOI: (10.1016/j.fertnstert.2010.12.019) Copyright © 2011 American Society for Reproductive Medicine Terms and Conditions

Figure 2 Positive control. Ovarian cortex from a 32-year-old patient with invasive ductal carcinoma. Ovarian cortex shows metastatic infiltration. (A) H&E. (B) WT-1. (C) CK-7. Magnification, ×10. Fertility and Sterility 2011 95, 2158-2161DOI: (10.1016/j.fertnstert.2010.12.019) Copyright © 2011 American Society for Reproductive Medicine Terms and Conditions