Volume 66, Issue 5, Pages (November 2014)

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Volume 66, Issue 5, Pages 884-893 (November 2014) Renal Tumor Contact Surface Area: A Novel Parameter for Predicting Complexity and Outcomes of Partial Nephrectomy Scott Leslie, Inderbir S. Gill, Andre Luis de Castro Abreu, Syed Rahmanuddin, Karanvir S. Gill, Mike Nguyen, Andre K. Berger, Alvin C. Goh, Jie Cai, Vinay A. Duddalwar, Monish Aron, Mihir M. Desai European Urology Volume 66, Issue 5, Pages 884-893 (November 2014) DOI: 10.1016/j.eururo.2014.03.010 Copyright © 2014 European Association of Urology Terms and Conditions

Fig. 1 (a) Measurement of tumor volume; (b) percentage of intraparenchymal component equals the intraparenchymal volume as a proportion of total tumor volume. European Urology 2014 66, 884-893DOI: (10.1016/j.eururo.2014.03.010) Copyright © 2014 European Association of Urology Terms and Conditions

Fig. 2 Total surface area. Calculations based on the formula for surface area of a sphere: 4πr2. European Urology 2014 66, 884-893DOI: (10.1016/j.eururo.2014.03.010) Copyright © 2014 European Association of Urology Terms and Conditions

Fig. 3 Contact surface area. European Urology 2014 66, 884-893DOI: (10.1016/j.eururo.2014.03.010) Copyright © 2014 European Association of Urology Terms and Conditions

Fig. 4 (a) Example of a 4-cm diameter exophytic tumor with a small contact surface area (CSA). Using Synapse 3D software, (A) total tumor volume and (B) intraparenchymal tumor volume were calculated to be 31.8ml and 5.8ml, respectively. (C) Total surface area (TSA) was 50.3cm2, derived from the formula for a sphere (4πr2), where r denotes radius (2cm). (D) CSA was 9.2cm2, calculated by multiplying TSA with percentage intraparenchymal component (18%). (b) Example of a 3.6-cm diameter endophytic tumor with a large CSA. Total tumor volume (A) and intra-parenchymal tumor volume (B) were calculated to be 25.1ml and 19.5ml, respectively. Tumor radius was 1.8cm, and calculated TSA was 40.7cm2 (C). Since the percent intra-parenchymal component was 78%, CSA was 31.6cm2 (D). European Urology 2014 66, 884-893DOI: (10.1016/j.eururo.2014.03.010) Copyright © 2014 European Association of Urology Terms and Conditions

Fig. 5 Contact surface area (CSA) and estimated blood loss (EBL). European Urology 2014 66, 884-893DOI: (10.1016/j.eururo.2014.03.010) Copyright © 2014 European Association of Urology Terms and Conditions

Fig. 6 Correlation between contact surface area and clinical parameters. EBL=estimated blood loss; eGFR=estimated glomerular filtration rate; LOS=length of stay. European Urology 2014 66, 884-893DOI: (10.1016/j.eururo.2014.03.010) Copyright © 2014 European Association of Urology Terms and Conditions