Defining study follow-up periods—index date (entry into cohort) and breaks in MSP registration. †End of follow-up due to earliest of: active TB diagnosis, death, end of MSP registration, or end of study period (31 December 2013). Defining study follow-up periods—index date (entry into cohort) and breaks in MSP registration. †End of follow-up due to earliest of: active TB diagnosis, death, end of MSP registration, or end of study period (31 December 2013). BC MSP, British Columbia Medical Services Plan (universal health insurance plan). Lisa A Ronald et al. BMJ Open 2016;6:e013488 ©2016 by British Medical Journal Publishing Group