(A) Immunohistochemistry of rat brainstem neurones reacting with anti-Hu antibodies showing strong nuclear staining and weaker cytoplasmic staining (counterstained.

Slides:

Advertisements

Similar presentations

Identification and validation of candidate biomarkers involved in human ovarian autoimmunity Purvi V. Mande, Firuza R. Parikh, Indira Hinduja, Kusum.

Advertisements

A Control B AD C Control D AD Non immunodepletion Non immunodepletion

Identification and validation of candidate biomarkers involved in human ovarian autoimmunity Purvi V. Mande, Firuza R. Parikh, Indira Hinduja, Kusum.

Hours after rec PR-Set7 release Ladder kDa 15 PR-Set7 Coomassie

Demonstration of Helicobacter pylori by the four staining methods: (A) modified Giemsa, (B) anti-H pylori antibody immunostain, (C) modified McMullen's.

Comparison of the banding patterns from randomly amplified polymorphic DNA PCR assays of sequential B pseudomallei isolates from each of the cases. Comparison.

Volume 60, Issue 2, Pages (August 2001)

Figure 1 Clinical correlates of neurodegeneration in MS

Sensory neuronopathy caused by dorsal root ganglionitis showing a hypercellular cluster of lymphocytes (nodule of Nageotte) indicating active neuronophagia.

AD AD E. coli J5 LPS (+) (-) Gram-negative LPS 25

Insulin regulates the expression and intra-membrane proteolysis of the recombinant HA-pSREBP-1c-Flag protein in McA-RH7777 cells Insulin regulates the.

(A) This 54 year old man with the flail arm syndrome has severe wasting of the arms causing profound weakness. (A) This 54 year old man with the flail.

(A, B). (A, B). Median motor nerve conduction study. Active recording electrode is over the APB muscle, with stimulation at the wrist, elbow, axilla,

These traces show typical electrophysiological features of a pre-synaptic neuromuscular transmission disorder in a patient with LEMS. The traces on the.

(A) EEG of a 75 year old woman with adult onset myoclonic epilepsy (see text, case 1), showing generalised spike and wave and polyspike and wave discharges.

Fig. 4. Identification of GRP78 as the target antigen of NMO-rAbs ON and ON Identification of GRP78 as the target antigen of NMO-rAbs.

The peptide arrays stained with ...

Figure 1 VGCC antibody uptake in cerebellar slice culture

Figure 1 Anti-LINGO-1 (Li81) has no effect on activated T-cell proliferation Anti-LINGO-1 (Li81) has no effect on activated T-cell proliferation (A) Western.

An example from a carotid surgery trial showing how an intention to treat analysis is less biased than an on-treatment analysis. An example from a carotid.

Schematic representation of the early M response from the distally propagated action potential and the later F wave from the proximally propagated action.

Histological and immunohistochemical evaluation of primary central nervous system lymphoma. Histological and immunohistochemical evaluation of primary.

Western blot analysis of histone H1.X.

(A) Normal repetitive nerve stimulation from abductor digiti minimi muscle in the hand. (A) Normal repetitive nerve stimulation from abductor digiti.

Eff localizes in many bands and interbands of wild-type polytene chromosomes. Eff localizes in many bands and interbands of wild-type polytene chromosomes.

Nerve conduction slowing and DRG sensory neuron and nuclear atrophy in 16-week-old diabetic mice. Nerve conduction slowing and DRG sensory neuron and nuclear.

Figure 2 Detection of atypical anti-neuronal antibodies Immunohistofluorescence assay on rat brain sagittal slices incubated with the patient's CSF and.

Autofluorescence left eye (case 3)

Schematic representation of phase cancellation and temporal dispersion in demyelination. Schematic representation of phase cancellation and temporal.

Fig. 1. p85β localizes at adhesion plaques and associates with FAK

Histone crotonylation in kidney tubular cells.

Vps36 interacts with Smo in the absence of Hh

Streptavidin identified in the vaccine protein profiles.

Receiver operating characteristics curves showing discrimination between patients with dementia of the Alzheimer type (at time of diagnosis) and non-demented.

Blood pressure and heart rate measured non-invasively continuously before, during, and after 60° head-up tilt (by the Portapres II) in a normal subject.

The superior quality of MRI over CT is demonstrated in this figure.

The effect on finger arterial blood pressure of (A) standing in the crossed leg position with leg muscle contraction, (B) sitting on a derby chair, and.

FIM total score by study visit (ITT population).

Illustration of the volumetric measures and correspondent anatomy.

Clinical overall score (COS), (A); cold detection thresholds (CDT), (B); warm detection thresholds (WDT), (C); and vibration thresholds (VT), (D) in patients.

Heavily T2-weighted MRI obtained with high resolution, showing multiple enlarged VRS, visible as well-demarcated CSF like structures, which, dependent.

Axial MRI of a 46 year old man with secondary progressive MS showing a large left sided periventricular lesion which is hyperintense with (A) T2 weighted.

(A) Axial FLAIR MRI reveals multiple areas of high signal intensity (arrows) in leptomeninges. (A) Axial FLAIR MRI reveals multiple areas of high signal.

Vincent van Gogh ( ). Vincent van Gogh ( ). Self portrait with bandaged ear (1889), courtesy of the Courthauld Institute, London. Van.

Specificity of the WDR81 antibody for the antigen.

Reactivity of the anti-p36 MAbs against whole M

α-Synuclein pathology in multiple system atrophy.

18F-dopa positron emission tomography (PET) in a normal subject, a patient with idiopathic Parkinson's disease (PD), and a patient with multiple system.

Left side: normal short latency somatosensory evoked potentials (SSEPSs) after stimulation of the median nerve (top picture) and posterior tibial nerve.

A, Northern blot analysis of DRCTNNB1A.

Examples of the visual rating scale for the medial and lateral temporal lobe on MR coronal images displayed conventionally with the letter on the right.

(A) High intensity lesions in the left dorsolateral midbrain on T2 weighted magnetic resonance imaging in case 1. (A) High intensity lesions in the left.

Frequency distribution of the number of fulfilled classification criteria for RA (ACR 1987) in relation to the proportion of positive anti-CCP antibodies.

Identification of the recombinant structural proteins expressed in recombinant baculovirus-infected Sf9 cells by immunofluorescence assay with rabbit anti-FMDV.

Figure 2. Histoimmunoprecipitation and antigen identification

Histograms showing periods until an improvement of one Hughes grade from onset. Histograms showing periods until an improvement of one Hughes grade from.

[123I]-FP-CIT (DaTSCAN) images demonstrating: (top left) normal tracer uptake in the putamen and caudate nuclei; then progressively decreasing uptake in.

Typical mean functional strength (where maximum function scores 5, and minimum scores zero; arithmetic mean of several activities plotted) against serum.

Kaplan-Meier table analysis of patients with corticobasal degeneration after onset of symptoms; the y axis refers to proportion of patients who are alive.

Lipocalin 2 (LCN2) protein was markedly upregulated in the brain 24 h after intraventricular haemoglobin injection compared with saline controls. Lipocalin.

Serial determinations of both anti-chromatin and anti-dsDNA antibodies in a patient who developed lupus nephropathy during the study period, showing that.

Conceptual diagram of dopaminergic system and disease and drug effects

MR thin (0.7 mm) CISS type sequences of the normal cerebello-pontine angles (A) axial and (B) coronal sections showing the cochlear nerve in the internal.

A reminder of the anatomy of the pons; although included to clarify the anatomical terms, a small lesion is in fact present, illustrating how easily such.

Axial magnetic resonance imaging (MRI) of a 30 year old man with relapsing remitting multiple sclerosis (MS) showing multiple periventricular lesions:

Axial T2-weighted MRI. (A and B) Dot-like hyperintensities characteristic of enlarged perivascular spaces (EPVS) in the basal ganglia in a patient with.

T2 weighted sagittal MR shows a Chiari I malformation with tonsillar ectopia (9 mm) at the cranio–cervical junction, resulting in disruption of normal.

Flow of recruitment: the screening and enrolment process for a 6-week randomised double-blind placebo-controlled feasibility trial in people with multiple.

Perimysial pathology in patients with selectively elevated aldolase.

Box plot showing the distribution of the TYM-MCI score for patients with SMC and aMCI/AD. aMCI/AD, amnestic mild cognitive impairment or Alzheimer’s disease;

Presentation transcript:

(A) Immunohistochemistry of rat brainstem neurones reacting with anti-Hu antibodies showing strong nuclear staining and weaker cytoplasmic staining (counterstained with H&E). (A) Immunohistochemistry of rat brainstem neurones reacting with anti-Hu antibodies showing strong nuclear staining and weaker cytoplasmic staining (counterstained with H&E). (B) A Western blotting of anti-Hu serum against recombinant Hu antigen demonstrating the typical ladder banding pattern (courtesy of E Amyes and Professor A Vincent, Institute of Molecular Medicine, Oxford). J H Rees J Neurol Neurosurg Psychiatry 2004;75:ii43-ii50 ©2004 by BMJ Publishing Group Ltd