Volume 2, Issue 3, Pages (September 2002)

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Volume 2, Issue 3, Pages 167-168 (September 2002) Blocking oncogenes in malignant cells by RNA interference—New hope for a highly specific cancer treatment? Arndt Borkhardt Cancer Cell Volume 2, Issue 3, Pages 167-168 (September 2002) DOI: 10.1016/S1535-6108(02)00129-0

Figure 1 Different mechanisms of oncogene activation in human tumors In cancer cells, proto-oncogenes have frequently been activated by various mechanisms, producing oncogenes that act in a dominant fashion. In epithelial tumors, point mutations are predominant whereas hematological malignancies often show gene fusions that result from chromosomal translocations. Cancer Cell 2002 2, 167-168DOI: (10.1016/S1535-6108(02)00129-0)