Quality of Life and Symptom Control after Stent Placement or Surgical Palliation of Malignant Colorectal Obstruction Satish Nagula, MD, Nicole Ishill,

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Quality of Life and Symptom Control after Stent Placement or Surgical Palliation of Malignant Colorectal Obstruction Satish Nagula, MD, Nicole Ishill, MS, Carla Nash, MD, Arnold J. Markowitz, MD, Mark A. Schattner, MD, Larissa Temple, MD, FACS, Martin R. Weiser, MD, FACS, Howard T. Thaler, PhD, Ann Zauber, PhD, Hans Gerdes, MD Journal of the American College of Surgeons Volume 210, Issue 1, Pages 45-53 (January 2010) DOI: 10.1016/j.jamcollsurg.2009.09.039 Copyright © 2010 American College of Surgeons Terms and Conditions

Figure 1 Patient flow diagram. Journal of the American College of Surgeons 2010 210, 45-53DOI: (10.1016/j.jamcollsurg.2009.09.039) Copyright © 2010 American College of Surgeons Terms and Conditions

Figure 2 Kaplan-Meier survival plots, starting 1 week after study enrollment. Median survival was 6 months for each group. Journal of the American College of Surgeons 2010 210, 45-53DOI: (10.1016/j.jamcollsurg.2009.09.039) Copyright © 2010 American College of Surgeons Terms and Conditions

Figure 3 Colon Obstruction Scores for stent and surgery groups (lower scores represent improved obstructive symptoms). Vertical bars represent interquartile range (IQR). Journal of the American College of Surgeons 2010 210, 45-53DOI: (10.1016/j.jamcollsurg.2009.09.039) Copyright © 2010 American College of Surgeons Terms and Conditions

Figure 4 Colon Obstruction Scores, stent patients only, colorectal cancer compared with extracolonic malignancies (lower scores represent improved obstructive symptoms). Vertical bars represent interquartile range (IQR). Journal of the American College of Surgeons 2010 210, 45-53DOI: (10.1016/j.jamcollsurg.2009.09.039) Copyright © 2010 American College of Surgeons Terms and Conditions

Figure 5 Composite Functional Assessment of Cancer Therapy-Colorectal (FACT-C) scores (higher scores represent improved quality of life). Vertical bars represent interquartile range (IQR). Journal of the American College of Surgeons 2010 210, 45-53DOI: (10.1016/j.jamcollsurg.2009.09.039) Copyright © 2010 American College of Surgeons Terms and Conditions

Figure 6 Colon Symptoms subscale of Functional Assessment of Cancer Therapy-Colorectal (higher scores represent improved quality of life). Vertical bars represent interquartile range (IQR). Journal of the American College of Surgeons 2010 210, 45-53DOI: (10.1016/j.jamcollsurg.2009.09.039) Copyright © 2010 American College of Surgeons Terms and Conditions

Figure 7 Self-reported quality of life (QoL; higher scores represent improved QoL). Vertical bars represent interquartile range (IQR). Journal of the American College of Surgeons 2010 210, 45-53DOI: (10.1016/j.jamcollsurg.2009.09.039) Copyright © 2010 American College of Surgeons Terms and Conditions