Nephrotoxicity of antiretroviral therapy in an HIV-infected patient

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Nephrotoxicity of antiretroviral therapy in an HIV-infected patient S.M. Said, S.H. Nasr, R. Samsa, G.S. Markowitz, V.D. D'Agati Kidney International Volume 71, Issue 10, Pages 1071-1075 (May 2007) DOI: 10.1038/sj.ki.5002134 Copyright © 2007 International Society of Nephrology Terms and Conditions

Figure 1 Renal biopsy findings. (a) A low-power view shows three tubules of probable distal or collecting tubular origin (arrows) containing abundant clear intraluminal crystals with needle and rod shapes surrounded by mononuclear cells and giant cells. The adjacent interstitium contains a dense infiltrate of mononuclear leukocytes (hematoxylin & eosin, original magnification × 200). (b) A high-power view illustrates the clear intratubular crystals (arrows) engulfed by intraluminal giant cells (arrowheads) (hematoxylin & eosin, original magnification × 400). Kidney International 2007 71, 1071-1075DOI: (10.1038/sj.ki.5002134) Copyright © 2007 International Society of Nephrology Terms and Conditions