Volume 150, Issue 7, Pages 1579-1589.e2 (June 2016) Terlipressin Plus Albumin Is More Effective Than Albumin Alone in Improving Renal Function in Patients With Cirrhosis and Hepatorenal Syndrome Type 1  Thomas D. Boyer, Arun J. Sanyal, Florence Wong, R. Todd Frederick, John R. Lake, Jacqueline G. O’Leary, Daniel Ganger, Khurram Jamil, Stephen Chris Pappas Samuel H. Sigal, Santiago J. Munoz, Vishal Patel, Paul Y. Kwo, Jasmohan S. Bajaj, Tarek I. Hassanein, Kirti Shetty, Rohit Satoskar, K. Rajender Reddy, Marlyn Mayo, Victor Araya, Nikroo Hashemi, Eyob Feyssa, Lorenzo Rossaro, David Kravetz, Priya Grewal, Ram Subramanian, Kevin Korenblat, Yuri Stepanovich Genyk, Fredric Regenstein, Joseph F. Buell, Nathan J. Shores, Sukru H. Emre, Andrea Duchini, Atif Zaman, Marco Antonio Olivera-Martinez, Michael K. Porayko, Alex S. Befeler, K. Gautham Reddy, Maria Del Pilar Hernandez, Stephen D. Zucker, Hugo E. Vargas, Michael Curry, Adnan Said, Kris V. Kowdley, Terry Box, David Shields Barnes, Marie Noëlle Pépin, Madhavi Rudraraju, Paul Angulo, Howard P. Monsour, David Wolf, Charles Howell, Fredric G. Regenstein, Antonio Sanchez, Hany Elbeshbeshy, Michael B. Fallon, Colin Swales, David A. Sass, Eva Urtasun Sotil, Brendan McGuire, Richard K. Gilroy, Juan A. Guerrero, Mark N. Wong, Obaid Shaikh, Stevan Gonzalez, Zeid Kayali Thomas D. Boyer, Arun J. Sanyal, Florence Wong, R. Todd Frederick, John R. Lake, Jacqueline G. O’Leary, Daniel Ganger, Khurram Jamil, Stephen Chris Pappas Samuel H. Sigal, Santiago J. Munoz, Vishal Patel, Paul Y. Kwo, Jasmohan S. Bajaj, Tarek I. Hassanein, Kirti Shetty, Rohit Satoskar, K. Rajender Reddy, Marlyn Mayo, Victor Araya, Nikroo Hashemi, Eyob Feyssa, Lorenzo Rossaro, David Kravetz, Priya Grewal, Ram Subramanian, Kevin Korenblat, Yuri Stepanovich Genyk, Fredric Regenstein, Joseph F. Buell, Nathan J. Shores, Sukru H. Emre, Andrea Duchini, Atif Zaman, Marco Antonio Olivera-Martinez, Michael K. Porayko, Alex S. Befeler, K. Gautham Reddy, Maria Del Pilar Hernandez, Stephen D. Zucker, Hugo E. Vargas, Michael Curry, Adnan Said, Kris V. Kowdley, Terry Box, David Shields Barnes, Marie Noëlle Pépin, Madhavi Rudraraju, Paul Angulo, Howard P. Monsour, David Wolf, Charles Howell, Fredric G. Regenstein, Antonio Sanchez, Hany Elbeshbeshy, Michael B. Fallon, Colin Swales, David A. Sass, Eva Urtasun Sotil, Brendan McGuire, Richard K. Gilroy, Juan A. Guerrero, Mark N. Wong, Obaid Shaikh, Stevan Gonzalez, Zeid Kayali  Gastroenterology  Volume 150, Issue 7, Pages 1579-1589.e2 (June 2016) DOI: 10.1053/j.gastro.2016.02.026 Copyright © 2016 AGA Institute Terms and Conditions

Figure 1 Correlation of SCr value with survival in overall patient population: percentage change from baseline to end of treatment in SCr vs percentage alive at day 90 (intent-to-treat population). Gastroenterology 2016 150, 1579-1589.e2DOI: (10.1053/j.gastro.2016.02.026) Copyright © 2016 AGA Institute Terms and Conditions

Figure 2 Cumulative incidence of renal replacement therapy. Gastroenterology 2016 150, 1579-1589.e2DOI: (10.1053/j.gastro.2016.02.026) Copyright © 2016 AGA Institute Terms and Conditions

Figure 3 (A) Overall survival for up to 90 days. P value is for terlipressin vs placebo from a 2-sample log-rank test stratified by qualifying SCr level and alcoholic hepatitis. (B) Overall survival for up to 90 days by treatment group and CHRSR status (intent-to-treat population). Gastroenterology 2016 150, 1579-1589.e2DOI: (10.1053/j.gastro.2016.02.026) Copyright © 2016 AGA Institute Terms and Conditions

Supplementary Figure 1 Patient disposition. Gastroenterology 2016 150, 1579-1589.e2DOI: (10.1053/j.gastro.2016.02.026) Copyright © 2016 AGA Institute Terms and Conditions