Hallmarks of Cancer Covered Sustain proliferative signaling-oncogenes Evade growth suppressors-tumor suppressor genes Enable replicative immortality- telomeres
Hallmarks of Cancer to Discover! Resist Cell Death Angiogenesis Metastasis and Invasion
Tumorigenesis
Tumorigenesis AKA carcinogenesis or oncogenesis literally the creation of cancer
Tumorigenesis Hyperplasia-too many cells resulting from uncontrolled cell division Appear normal, but there is loss of control of growth
Tumorigenesis Dysplasia-further growth, some abnormal changes to cell
Tumorigenesis Anaplasia-cells become more abnormal and spread over wider area of tissue Cells lose their original function