Hallmarks of Cancer Covered

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Presentation transcript:

Hallmarks of Cancer Covered Sustain proliferative signaling-oncogenes Evade growth suppressors-tumor suppressor genes Enable replicative immortality- telomeres

Hallmarks of Cancer to Discover! Resist Cell Death Angiogenesis Metastasis and Invasion

Tumorigenesis

Tumorigenesis AKA carcinogenesis or oncogenesis literally the creation of cancer

Tumorigenesis Hyperplasia-too many cells resulting from uncontrolled cell division Appear normal, but there is loss of control of growth

Tumorigenesis Dysplasia-further growth, some abnormal changes to cell

Tumorigenesis Anaplasia-cells become more abnormal and spread over wider area of tissue Cells lose their original function