Protein Synthesis Part 2

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Protein Synthesis Part 2 AP Biology Protein Synthesis Part 2

Peptide Bonding

2’ structure

3’ Structure

Translation by the Ribosome

Transfer RNA (tRNA)

Transfer RNA in 3D

Amino Acid Codon Chart

Anti-codon matches the codon

Connecting tRNA with Amino Acid

Ribosome Structure

Initiation “Build the factory”

Elongation of the peptide & Translocation

Peptide Bonding Upclose

Termination of translation

3’ T A C C A G C C G G T A A T A G G G A C C A T T 5’ DNA TEMPLATE 5’ A U G G U C G G C C A U U A U C C C U G G U A A 3’ mRNA METH VAL GLY __ HIST TYR __ PRO TRP __ __ ___ ___ PROTEIN 3’ U A C C A G C C G G U A A U A G G G A C C A U U 5’ ANTI – CODON Sequence Does the DNA Sequence (Million Dollar Blueprint) look like the Anti-codon Sequence? Remember, this is how the ribosome “knew” the Amino Acid was Correct.

Polyribosomes

Chaperonin Protein will stay in the cell

RER & SRP Protein will leave the cell

The BIG Picture