Nat. Rev. Endocrinol. doi:10.1038/nrendo.2016.12 Figure 4 Cre-mediated gene recombination in subpopulations of bone cell lineages Figure 4 | Cre-mediated gene recombination in subpopulations of bone cell lineages. Expression of Tomato and green fluorescent protein (GFP) reporter proteins in hindlimbs of transgenic mice marks specific skeletal populations targeted by different Cre drivers. a | TdTomatoFlox/+; Prx1–Cre (P0). b | TdTomatoFlox/+; Osx1–Cre (P14). c | mTomato/mGFPFlox/+; Gdf5–Cre (P0). Longitudinal sections of the hindlimb were imaged for red fluorescent protein, GFP and 4′,6-diamidino-2-phenylindole. Gamer, L. W. & Rosen, V. et al. (2016) BMP signalling in skeletal development, disease and repair Nat. Rev. Endocrinol. doi:10.1038/nrendo.2016.12