Persistent Pain: A Disease Entity

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Presentation transcript:

Persistent Pain: A Disease Entity Michael J. Cousins, AM, MD, FANZCA, FRCA, FFPMANZCA, FAChPM (RACP) Journal of Pain and Symptom Management Volume 33, Issue 2, Pages S4-S10 (February 2007) DOI: 10.1016/j.jpainsymman.2006.09.007 Copyright © 2007 U.S. Cancer Pain Relief Committee Terms and Conditions

Fig. 1 Ectopic activity in primary afferents after injury (adapted with permission14). Journal of Pain and Symptom Management 2007 33, S4-S10DOI: (10.1016/j.jpainsymman.2006.09.007) Copyright © 2007 U.S. Cancer Pain Relief Committee Terms and Conditions

Fig. 2 Sprouting of the sympathetic nerve efferents (adapted with permission14). Journal of Pain and Symptom Management 2007 33, S4-S10DOI: (10.1016/j.jpainsymman.2006.09.007) Copyright © 2007 U.S. Cancer Pain Relief Committee Terms and Conditions

Fig. 3 Spinal cord events that perpetuate pain. Developed from a slide presentation delivered at IASP 2005, Sydney, Australia. Journal of Pain and Symptom Management 2007 33, S4-S10DOI: (10.1016/j.jpainsymman.2006.09.007) Copyright © 2007 U.S. Cancer Pain Relief Committee Terms and Conditions

Fig. 4 Pathophysiology of hyperalgesia and allodynia. Developed from a slide presentation delivered at IASP 2005, Sydney, Australia. Journal of Pain and Symptom Management 2007 33, S4-S10DOI: (10.1016/j.jpainsymman.2006.09.007) Copyright © 2007 U.S. Cancer Pain Relief Committee Terms and Conditions

Fig. 5 After discharges to innocuous mechanical stimulation in a contusion model of neuropathic pain after spinal cord injury.40 Journal of Pain and Symptom Management 2007 33, S4-S10DOI: (10.1016/j.jpainsymman.2006.09.007) Copyright © 2007 U.S. Cancer Pain Relief Committee Terms and Conditions