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Nat. Rev. Cardiol. doi:10.1038/nrcardio.2017.65 Figure 9 Comparative mortality in HFpEF and HFrEF from the MAGGIC study Figure 9 | Comparative mortality in HFpEF and HFrEF from the MAGGIC study51. a | Age-adjusted and comorbidity-adjusted all-cause mortality in heart failure with preserved ejection fraction (HFpEF) and heart failure with reduced ejection fraction (HFrEF) are shown. b | Adjusted hazard ratios for mortality in HFpEF versus HFrEF according to types of studies (randomized clinical trials [RCT] or observational studies [OBS]) are shown along with the adjusted annualized mortality. c | Effect of lower ejection fraction (EF; relative to an EF ≥60%) on adjusted risk of all-cause (left) and cardiovascular (right) death. Panels a and c modified from Meta-analysis Global Group in Chronic Heart Failure. The survival of patients with heart failure with preserved or reduced left ventricular ejection fraction: an individual patient data meta-analysis. Eur. Heart J. 33 (14), 1750–1757 (2012), with permission from Oxford University Press and the European Society of Cardiology. Panels a and c modified from Meta-analysis Global Group in Chronic Heart Failure. The survival of patients with heart failure with preserved or reduced left ventricular ejection fraction: an individual patient data meta-analysis. Eur. Heart J. 33 (14), 1750–1757 (2012), with permission from Oxford University Press and the European Society of Cardiology Dunlay, S. M. et al. (2017) Epidemiology of heart failure with preserved ejection fraction Nat. Rev. Cardiol. doi:10.1038/nrcardio.2017.65