Nat. Rev. Cardiol. doi:10.1038/nrcardio.2017.94 Figure 3 Temporal relationship between CIED-detected AHREs and stroke or systemic embolism Figure 3 | Temporal relationship between CIED-detected AHREs and stroke or systemic embolism. Data from the IMPACT trial44. Each horizontal line represents an individual patient, with the time of stroke or systemic embolism indicated by the vertical line. The grey bars represent the duration of cardiac implanted electronic device (CIED) implantation before and after the stroke. Red bars indicate patients with no atrial high-rate episodes (AHREs) before the stroke (9 out of 29 patients had AHREs noted only after the event). No AHREs occurred during the entire monitoring period in 40 patients with thromboembolic events (not shown). Dark grey vertical lines within each horizontal bar represent AHREs, and the height of these thin vertical lines represent the AHRE duration. Oral anticoagulation starts at the green asterisks and stops at the red asterisks. Modified from Martin, D. T. et al. Randomized trial of atrial arrhythmia monitoring to guide anticoagulation in patients with implanted defibrillator and cardiac resynchronization devices. Eur. Heart J. 36 (26), 1660–1668 (2015), with permission from Oxford University Press and the European Society of Cardiology. Modified from Martin, D. T. et al. Randomized trial of atrial arrhythmia monitoring to guide anticoagulation in patients with implanted defibrillator and cardiac resynchronization devices. Eur. Heart J. 36 (26), 1660–1668 (2015), with permission from Oxford University Press and the European Society of Cardiology Freedman, B. et al. (2017) Management of atrial high-rate episodes detected by cardiac implanted electronic devices Nat. Rev. Cardiol. doi:10.1038/nrcardio.2017.94