Single and Multiple Dose MultiStem (Multipotent Adult Progenitor Cell) Therapy Prophylaxis of Acute Graft-versus-Host Disease in Myeloablative Allogeneic.

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Single and Multiple Dose MultiStem (Multipotent Adult Progenitor Cell) Therapy Prophylaxis of Acute Graft-versus-Host Disease in Myeloablative Allogeneic Hematopoietic Cell Transplantation: A Phase 1 Trial Richard T. Maziarz, Timothy Devos, Carlos R. Bachier, Steven C. Goldstein, Jose F. Leis, Steven M. Devine, Gabrielle Meyers, James L. Gajewski, Johan Maertens, Robert J. Deans, Wouter Van't Hof, Hillard M. Lazarus Biology of Blood and Marrow Transplantation Volume 21, Issue 4, Pages 720-728 (April 2015) DOI: 10.1016/j.bbmt.2014.12.025 Copyright © 2015 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 1 Cumulative incidences of acute GVHD after MAPC product therapy observed in study patients. Grades II to IV (solid line) and III and IV GVHD (broken line) are shown for all patients on study (A). Grade II to IV GVHD (B,C) and grade III and IV GVHD incidences (D,E) are presented for all dose, single, and repeat-dose groups, respectively. Biology of Blood and Marrow Transplantation 2015 21, 720-728DOI: (10.1016/j.bbmt.2014.12.025) Copyright © 2015 American Society for Blood and Marrow Transplantation Terms and Conditions