Course of Immunology - introduction (2017/2018) Marta Sobotková email: marta.sobotkova@fnmotol.cz

Course structure ● Lectures Presence in lectures is obligatory Lectures are held every Tuesday at 8:00-9:40 Small Left Lecture Hall - Three absences are tolerated, more frequent absences must be based on official certificate and will be solved individually

Course structure ● Seminars - The first seminar and presentation of your thesis are compulsory; the time of other seminars is devoted to self-studying, preparation of seminar thesis and consultations with teachers

Seminar thesis ● groups of 1-3 students ● drawing of topics today List of topics can be found on our website

Seminar thesis ● structure of thesis and contemporary contents: title names of authors with study group numbers contact email abstract (250 words max.) 1000 – 2000 words references form of an essay briefly & concisely & interestingly in the digital form (doc, docx form preffered) - has to be sent to: irena.novakova@lfmotol.cuni.cz

Seminar thesis ● consultations with assigned teacher ●term of submission: until 28.10.2018 in the digital form (doc, docx form preffered) has to be sent to: your assigned teacher and michaela.kratochvilova@lfmotol.cuni.cz

Oral presentations November 22n, 29t and December 6 time 8.00-9.40 November 23, 30 and December 7 - each thesis will be presented verbally - range: 8 minutes Powerpoint presentation (6-10 slides)

Final appraisal ● Presence on lectures ● Seminar thesis: fulfilled / not fulfilled + verbal appraisal (after presentation) ● Verbal examination: 2 out of 50 questions

Evaluation of the essay: 1/ Adherence to the length limits 2/ Correct content of the essay, no serious misunderstandings 3/ Satisfactory graphical layout and style of the essay Other comments: Evaluation of the verbal presentation: 3/ Satisfactory graphical layout and style of the presentation

http://imunologie.lf2.cuni.cz/ ● shedules ● presentations (download possible) ● recommended literature, links ● contacts

Citation Most of the patients are hemizygous for 22q11.2, some have defects in various loci on chromosome 10, about 10% of cases are familial (2, 3). Literature / References: 2. DRISCOLL DA, SALVIN J, SELLINGER B, et al. Prevalence of 22q11 microdeletions in DiGeorge and velocardiofacial syndromes: implications for genetic counselling and prenatal diagnosis. J Med Genet 1993: 30: 813-7. 3. SEDIVA A, BARTUNKOVA J, ZACHOVA R, et al. Early development of immunity in diGeorge syndrome. Med Sci Monit 2005: 11: 182-7.

Sources Bibliographic databases Clinical sources online

Pubmed – www.pubmed.com

Medscape - www.emedicine.com

Up-to-date – www.uptodate.com

Orphanet – www.orpha.net

Good luck with Your essays and presentations ! Marta Sobotková email: marta.sobotkova@fnmotol.cz