Chronic Histological Transmurality of High-Intensity Focused Ultrasound Ablation Paolo Vanelli, MD, Roberta Rossi, MD, Guido Gelpi, MD, Giovanni Cagnoni,

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Chronic Histological Transmurality of High-Intensity Focused Ultrasound Ablation Paolo Vanelli, MD, Roberta Rossi, MD, Guido Gelpi, MD, Giovanni Cagnoni, MD, Monica Contino, MD, Enrica Bosisio, MD, Gianluca Vago, MD, Carlo Antona, MD The Annals of Thoracic Surgery Volume 93, Issue 6, Pages 2053-2056 (June 2012) DOI: 10.1016/j.athoracsur.2011.11.065 Copyright © 2012 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Left atrial ablation and quadrant wall sample collection. (Ao = Aorta; CS = coronary sinus; IVC = inferior vena cava; LIPV = left inferior pulmonary vein; LSPV = left superior pulmonary vein; Pa = pulmonary artery; RIPV = right inferior pulmonary vein; RSPV = right superior pulmonary vein; SVC = superior vena cava.) The Annals of Thoracic Surgery 2012 93, 2053-2056DOI: (10.1016/j.athoracsur.2011.11.065) Copyright © 2012 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Macroscopic findings of left atrial ablation. (CS = coronary sinus; EnC = endocardium; EpC = epicardium.) The Annals of Thoracic Surgery 2012 93, 2053-2056DOI: (10.1016/j.athoracsur.2011.11.065) Copyright © 2012 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 Histologic study of a transmural cross-section collected from the atrial wall. Damage to cardiomyocytes is evident over full thickness of the transmural sample (hematoxylin and eosin, ×40 [A]; Masson trichrome, ×40 [B]). The Annals of Thoracic Surgery 2012 93, 2053-2056DOI: (10.1016/j.athoracsur.2011.11.065) Copyright © 2012 The Society of Thoracic Surgeons Terms and Conditions