Ebola control: effect of asymptomatic infection and acquired immunity

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Ebola control: effect of asymptomatic infection and acquired immunity Steve E Bellan, Juliet R C Pulliam, Jonathan Dushoff, Lauren Ancel Meyers  The Lancet  Volume 384, Issue 9953, Pages 1499-1500 (October 2014) DOI: 10.1016/S0140-6736(14)61839-0 Copyright © 2014 Elsevier Ltd Terms and Conditions

Figure Effects of immunising asymptomatic infections on Liberia outbreak projections Projected cumulative incidence including and excluding asymptomatic infection. If 50% of infections are asymptomatic, then models overlooking asymptomatic infection will overestimate disease incidence later in the epidemic, as individuals who were asymptomatically infected become immune and contribute to herd immunity. By Jan 10, 2015 (red vertical line) models ignoring asymptomatic immunity overestimate cumulative incidence by 50% (red). The code for models and calculations are from the Ebola code repository. The Lancet 2014 384, 1499-1500DOI: (10.1016/S0140-6736(14)61839-0) Copyright © 2014 Elsevier Ltd Terms and Conditions