Real-time PCR assay-based strategy for differentiation between active Pneumocystis jirovecii pneumonia and colonization in immunocompromised patients

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Real-time PCR assay-based strategy for differentiation between active Pneumocystis jirovecii pneumonia and colonization in immunocompromised patients A. Alanio, G. Desoubeaux, C. Sarfati, S. Hamane, A. Bergeron, E. Azoulay, J.M. Molina, F. Derouin, J. Menotti Clinical Microbiology and Infection Volume 17, Issue 10, Pages 1531-1537 (October 2011) DOI: 10.1111/j.1469-0691.2010.03400.x Copyright © 2011 European Society of Clinical Infectious Diseases Terms and Conditions

FIG. 1 Pneumocystis jirovecii DNA quantification by real-time PCR according to the clinical probability of Pneumocystis pneumonia (PCP) in induced sputa (IS) and bronchoalveolar lavage (BAL) samples (a) and in human immunodeficiency virus (HIV)-infected and non-HIV-infected immunocompromised patients (b). Thick horizontal bars represent median values. HP, high probability; LP, low probability; TFEq, trophic form equivalents. Clinical Microbiology and Infection 2011 17, 1531-1537DOI: (10.1111/j.1469-0691.2010.03400.x) Copyright © 2011 European Society of Clinical Infectious Diseases Terms and Conditions

FIG. 2 Receiver operator characteristic curve of real-time PCR for Pneumocystis pneumonia (PCP) diagnosis. TFEq, trophic form equivalents. Clinical Microbiology and Infection 2011 17, 1531-1537DOI: (10.1111/j.1469-0691.2010.03400.x) Copyright © 2011 European Society of Clinical Infectious Diseases Terms and Conditions