Kai Papenfort, Jörg Vogel Molecular Cell

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Presentation transcript:

Sweet Business: Spot42 RNA Networks with CRP to Modulate Catabolite Repression Kai Papenfort, Jörg Vogel Molecular Cell Volume 41, Issue 3, Pages 245-246 (February 2011) DOI: 10.1016/j.molcel.2011.01.011 Copyright © 2011 Elsevier Inc. Terms and Conditions

Figure 1 Catabolite Repression as an sRNA-Controlled Multioutput Feedforward Loop The CRP transcriptional regulator (light green) negatively controls the expression of the Spot42 sRNA (orange), which itself acts as a posttranscriptional regulator of multiple target genes of various regulons (red, sugar transport; green, sugar catabolism; blue, central/secondary metabolism; orange, redox balancing; purple, antioxidant biosynthesis; light blue, unknown). Expression of half of the Spot42 target genes is transcriptionally controlled by CRP. Solid lines indicate transcriptional control; dashed lines, posttranscriptional regulation. Molecular Cell 2011 41, 245-246DOI: (10.1016/j.molcel.2011.01.011) Copyright © 2011 Elsevier Inc. Terms and Conditions