TGFβ Signaling: Receptors, Transducers, and Mad Proteins

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TGFβ Signaling: Receptors, Transducers, and Mad Proteins Joan Massagué  Cell  Volume 85, Issue 7, Pages 947-950 (June 1996) DOI: 10.1016/S0092-8674(00)81296-9

Figure 1 Steps in TGFβ Receptor Activation and Signal Transduction Cell 1996 85, 947-950DOI: (10.1016/S0092-8674(00)81296-9)

Figure 2 Ligand–Receptor Combinations and Their Known Effects The TGFβ family tree lists only representative members of each cluster of isoforms. All the components listed are mammalian except DPP and its receptors. Cell 1996 85, 947-950DOI: (10.1016/S0092-8674(00)81296-9)

Figure 3 Domain Structure of Mad Proteins and Similarity among Family Members The structures are aligned based on a highly conserved N-terminal motif (LVKKLKK). The level of identity refers to the combined N- and C-domains and excludes other regions. Cell 1996 85, 947-950DOI: (10.1016/S0092-8674(00)81296-9)