Clostridium difficile Infection after Allogeneic Hematopoietic Stem Cell Transplantation: Incidence, Risk Factors, and Outcome Lise Willems, Raphaël.

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Clostridium difficile Infection after Allogeneic Hematopoietic Stem Cell Transplantation: Incidence, Risk Factors, and Outcome Lise Willems, Raphaël Porcher, Matthieu Lafaurie, Isabelle Casin, Marie Robin, Aliénor Xhaard, Anna Lisa Andreoli, Paula Rodriguez- Otero, Nathalie Dhedin, Gérard Socié, Patricia Ribaud, Régis Peffault de Latour Biology of Blood and Marrow Transplantation Volume 18, Issue 8, Pages 1295-1301 (August 2012) DOI: 10.1016/j.bbmt.2012.02.010 Copyright © 2012 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 1 Cumulative hazard of Clostridium difficile infection (CDI) after hematopoietic stem cell transplantation (HSCT). The black curve represents the non-parametric estimate of the cumulative hazard of CDI after HSCT, and the grey curve represents the estimate obtained assuming piecewise constant hazards on 3 separate periods. Incidence was 61 of 10,000 patient-days during the first week after HSCT, 12 of 10,000 patient-days from week 1 to week 8, and 1.6 of 10,000 patient-days from week 8 to week 52 after HSCT. Biology of Blood and Marrow Transplantation 2012 18, 1295-1301DOI: (10.1016/j.bbmt.2012.02.010) Copyright © 2012 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 2 Overall survival of patients with or without Clostridium difficile infection (CDI) after hematopoietic stem cell transplantation (HSCT). Patients with CDI are represented in the gray line (n = 53), whereas others are represented in the black line (n = 354). Biology of Blood and Marrow Transplantation 2012 18, 1295-1301DOI: (10.1016/j.bbmt.2012.02.010) Copyright © 2012 American Society for Blood and Marrow Transplantation Terms and Conditions