A Rarity in a Common Disease: Thyroid Paraganglioma

Slides:

Advertisements

Similar presentations

Low-Dose Aspirin in Patients with Stable Cardiovascular Disease: A Meta-analysis Jeffrey S. Berger, MD, MS, David L. Brown, MD, Richard C. Becker, MD The.

Advertisements

Renal Cell Carcinoma: Delayed Metachronous Metastases to Parotid and Cerebellum Antonia Kolokythas, DDS, MSc, Scott Weiskopf, DDS, Manmeet Singh, DO,

Pleomorphic Adenoma of the Parotid Gland

The Autopsy of Chicken Nuggets Reads “Chicken Little”

Volume 3, Issue 5, Pages (September 2017)

An Unusual Cause of Leg Ulcerations

A Handy Clue: Palmar Fasciitis and Polyarthritis Syndrome

Restoring Balance: Paraneoplastic Cerebellar Degeneration

A Pain in the Neck: Thyroid Abscess

Not Your Typical Renal Cyst

Intravascular Large B Cell Lymphoma Presenting as Transient Erythema Nodosum-Like Lesions and Fever David J. Tsoulis, MD, Danny Ghazarian, MD, Eugenia.

Cholangiocarcinoma Presenting as Metastases to the Cervical Spine

Was It the Zebu? The American Journal of Medicine

One Appendix, Two Different Pains

An Iatrogenic Metastasis

Luis H. Camacho, MD, MPH, Ana Mora-Bowen, MS, Reginald Munden, MD, W

Bilateral Adrenal Adenomas and Persistent Leukocytosis: A Unique Case of Cushing’s Syndrome Nilay Desai, MD, Anoop Kapoor, MD, Binod K. Singh, MD, Jingxuan.

Pleomorphic Adenoma of the Parotid Gland

Freebie Rhabdomyolysis: A Public Health Concern

Primary thyroid marginal zone B-cell lymphoma in a patient with psoriatic arthritis treated with etanercept Hyunju Jin, MD, Hyun-Ho Cho, MD, Won-Jeong.

Quiz Page March 2008 American Journal of Kidney Diseases

An Uncommon Cause of Obstructive Jaundice: An Infrequent Neoplasm

Major response to vemurafenib in patient with severe cutaneous Langerhans cell histiocytosis harboring BRAF V600E mutation Julie Charles, MD, PhD, Jean-Claude.

Beta-human Chorionic Gonadotropin-producing Renal Cell Carcinoma

A paraganglioma parasitizing the left circumflex coronary artery

Robert Goulden, MBBS, MSc, MPhil, MA The American Journal of Medicine

Height Loss and Generalized Pain in a 35-year-old Man

Symptomatic, Obstructive Cardiac Metastasis Can Respond to Chemotherapy Matthew Cove, MD, Ruth Johnston, MD, Richard Cowan, MD, Philip Haji-Michael, MD

Ashok K. Malani, MD, MS, Brian Olofsson, MD, David Debono, MD

Gynecomastia: Look Beyond the Obvious

Hypokalemic Periodic Paralysis due to Graves Disease

The Reply The American Journal of Medicine

Jessica L. Lee, MD, MS, Esther S. Oh, MD, Rebecca W. Lee, MD, Thomas E

Scrotal Swelling and Sarcoidosis

Disseminated Mycobacterium avium-intracellulare Complex Infection

Significant Aspirations: Recurrent Pneumonia

Diabetic Muscle Infarction: Case Report of a Rare Complication

Lump in Scrotum and Abnormal Chest X-Ray: What Is the Link?

A Diagnostic Dilemma in a Patient with Polyarthritis

Gastrointestinal Bleeding: One Complaint, Two Culprits

Solitary Lung Masses Due to Occult Aspiration

The Autopsy of Chicken Nuggets Reads “Chicken Little”

Quiz Page December 2008 American Journal of Kidney Diseases

Adnan M. Al-Ayoubi, MD, Jonathan S. Ralston, MD, S

Quiz Page September 2009 American Journal of Kidney Diseases

Bronchial Oncocytoma With High 18F-Fluorodeoxyglucose Uptake Revealed by Nephrotic Syndrome Giovanni Leuzzi, MD, Alfredo Cesario, MD, Marco Chiappetta,

Unusual Cause of Stridor in an 80-Year-old Man

A Gut Feeling The American Journal of Medicine

Pulmonary Langerhans' Cell Histiocytosis

Diabetic Mastopathy Masquerading as Breast Cancer

Vanessa Rodriguez, MD, Rita L. Romaguera, MD, Bettina Heidecker, MD

The Heart of the Matter The American Journal of Medicine

Axillary Mass and Hypercalcemia: The Value of a Physical Examination

Exogenous Lipoid Pneumonia (Fire-eater's Lung)

A 64-Year-Old Woman With an Incidental Pulmonary Nodule

Eagle's Syndrome The American Journal of Medicine

Ajay Major, MD, MBA, Mel Anderson, MD The American Journal of Medicine

Plasma Lactescence in Acute Pancreatitis

Pheochromocytoma Presenting as Fever of Unknown Origin

Quiz American Journal of Kidney Diseases

Waxing and Waning Lymphadenopathy

Trends in Prolonged Hospitalizations in the United States from 2001 to 2012: A Longitudinal Cohort Study Lauren Doctoroff, MD, Douglas J. Hsu, MD, Kenneth.

Evangelos V. Koutis, MD, Dimitrios A. Assimakopoulos, MD, Michel G

Painful Violaceous Purpura on a 44-Year-Old Woman

Quiz Page January 2010 American Journal of Kidney Diseases

Falls in Older Adults: Risk Assessment, Management and Prevention

Provoked Dizziness from Bow Hunter's Syndrome

Acute renal failure due to the herbal remedy CKLS

Toward a More Responsible News Media

Hypophosphatemia: Diagnostic Significance in Legionnaires’ Disease

Presentation transcript:

A Rarity in a Common Disease: Thyroid Paraganglioma Jutarat Sangtian, MD, Maria Rae Evasovich, MD, Tasma Harindhanavudhi, MD The American Journal of Medicine Volume 130, Issue 4, Pages e133-e135 (April 2017) DOI: 10.1016/j.amjmed.2016.11.030 Copyright © 2016 Elsevier Inc. Terms and Conditions

Figure 1 Thyroid ultrasound demonstrated a large complex nodule measuring 6.6 × 4.5 × 3.3 cm with central internal blood flow that occupied almost the entire left thyroid lobe. The American Journal of Medicine 2017 130, e133-e135DOI: (10.1016/j.amjmed.2016.11.030) Copyright © 2016 Elsevier Inc. Terms and Conditions

Figure 2 Fine-needle aspiration of the left solitary thyroid nodule revealed groups of benign epithelial cells and colloid in the background (Wright stain). The American Journal of Medicine 2017 130, e133-e135DOI: (10.1016/j.amjmed.2016.11.030) Copyright © 2016 Elsevier Inc. Terms and Conditions

Figure 3 Hematoxylin & eosin-stained section of the specimen revealed tumor arranged in organoid vascularized pattern, with Zellballen architecture comprised of central cells with often highly pleomorphic enlarged nuclei and abundant eosinophilic and vacuolized cytoplasm, surrounded by spindle sustentacular cells (20× magnification). The American Journal of Medicine 2017 130, e133-e135DOI: (10.1016/j.amjmed.2016.11.030) Copyright © 2016 Elsevier Inc. Terms and Conditions

Figure 4 Immunohistochemical stains of the specimen revealed positivity of chromogranin (label A) and synaptophysin (label B) in organoid neoplastic cells and S100 (label C) highlighted sustentacular cells. The American Journal of Medicine 2017 130, e133-e135DOI: (10.1016/j.amjmed.2016.11.030) Copyright © 2016 Elsevier Inc. Terms and Conditions