Expression of cyclooxygenase-2 and vascular endothelial growth factor in ovarian endometriotic cysts and their relationship with angiogenesis Seyit Temel Ceyhan, M.D., Onder Onguru, M.D., İskender Baser, M.D., Omer Gunhan, D.D. Fertility and Sterility Volume 90, Issue 4, Pages 988-993 (October 2008) DOI: 10.1016/j.fertnstert.2007.07.1332 Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions
Figure 1 (A) Microvessel proliferation in endometriosis immunohistochemically stained with CD34 (immunohistochemistry × 50). (B) Moderate to strong Cox-2 expression in epithelial cells in endometriosis. Hemosiderin-laden macrophages beneath surface epithelium were negative for Cox-2 (immunohistochemistry × 100). (C) Strong Cox-2 expression in another case of endometriosis (immunohistochemistry ×100). (D) Mild VEGF expression was present in epithelial cells in some cases of endometriosis (immunohistochemistry × 100). (E) Moderate VEGF expression was usual in stromal cells in endometriosis (immunohistochemistry ×100). (F) Strong VEGF expression was also observed in stromal cells in endometriosis (immunohistochemistry × 100). In this case, VEGF expression was also present in epithelial cells. Fertility and Sterility 2008 90, 988-993DOI: (10.1016/j.fertnstert.2007.07.1332) Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions