Closed-loop insulin delivery in inpatients with type 2 diabetes: a randomised, parallel- group trial Hood Thabit, PhD, Sara Hartnell, BSc, Janet M Allen,

Slides:

Advertisements

Similar presentations

Overnight Closed-Loop Insulin Delivery in Young People With Type 1 Diabetes: A Free- Living, Randomized Clinical Trial Featured Article: Roman Hovorka,

Advertisements

2 month evening and night closed-loop glucose control in patients with type 1 diabetes under free-living conditions: a randomised crossover trial Dr.

Volume 384, Issue 9961, Pages (December 2014)

Pharmacogenetics and future drug development and delivery

Food systems, nutrition, health and the environment

Effect of a bereavement support group on female adolescents' psychological health: a randomised controlled trial in South Africa Prof Tonya Renee Thurman,

Volume 388, Issue 10058, Pages (November 2016)

Levels and trends in contraceptive prevalence, unmet need, and demand for family planning for 29 states and union territories in India: a modelling study.

Disparities and change over time in distance women would need to travel to have an abortion in the USA: a spatial analysis Dr Jonathan M Bearak, PhD,

New Developments in Insulin Therapy for Type 2 Diabetes

Total and cause-specific mortality before and after the onset of the Greek economic crisis: an interrupted time-series analysis Ioannis Laliotis, PhD,

A mindfulness-based intervention to increase resilience to stress in university students (the Mindful Student Study): a pragmatic randomised controlled.

The commercial determinants of health

Home use of closed-loop insulin delivery for overnight glucose control in adults with type 1 diabetes: a 4-week, multicentre, randomised crossover study

Day-and-night glycaemic control with closed-loop insulin delivery versus conventional insulin pump therapy in free-living adults with well controlled.

Helen Cox, Mark P Nicol The Lancet Infectious Diseases

Threats to human health by great ocean garbage patches

Volume 388, Issue 10052, Pages (October 2016)

An internet-based intervention with brief nurse support to manage obesity in primary care (POWeR+): a pragmatic, parallel-group, randomised controlled.

Pneumococcal conjugate vaccine 13 delivered as one primary and one booster dose (1 + 1) compared with two primary doses and a booster (2 + 1) in UK infants:

Home use of closed-loop insulin delivery for overnight glucose control in adults with type 1 diabetes: a 4-week, multicentre, randomised crossover study

Do air quality alerts benefit public health? New evidence from Canada

Volume 389, Issue 10071, Pages (February 2017)

Nicola Low, Joost H Smid The Lancet Public Health

Efficacy of chlorhexidine application to umbilical cord on neonatal mortality in Pemba, Tanzania: a community-based randomised controlled trial Dr Sunil.

Volume 375, Issue 9716, Pages (February 2010)

Effective cross-sector collaborations create sustainability

Volume 392, Issue 10141, Pages (July 2018)

Retracted: Worldwide burden of cancer attributable to diabetes and high body-mass index: a comparative risk assessment Jonathan Pearson-Stuttard, BMBCh,

Volume 4, Issue 2, Pages (February 2017)

Volume 4, Issue 6, Pages (June 2017)

Disparities and change over time in distance women would need to travel to have an abortion in the USA: a spatial analysis Dr Jonathan M Bearak, PhD,

Volume 392, Issue 10155, Pages (October 2018)

Food systems, nutrition, health and the environment

Changes in chlamydia prevalence and duration of infection estimated from testing and diagnosis rates in England: a model-based analysis using surveillance.

Sherif M Abdalla, Robert Bortolussi, Noni E MacDonald

Effectiveness of a lifestyle intervention led by female community health volunteers versus usual care in blood pressure reduction (COBIN): an open-label,

Volume 388, Issue 10058, Pages (November 2016)

Risk of poor development in young children in low-income and middle-income countries: an estimation and analysis at the global, regional, and country.

Levels and trends in contraceptive prevalence, unmet need, and demand for family planning for 29 states and union territories in India: a modelling study.

Volume 5, Issue 8, Pages (August 2018)

Retracted: Worldwide burden of cancer attributable to diabetes and high body-mass index: a comparative risk assessment Jonathan Pearson-Stuttard, BMBCh,

Effect of a bereavement support group on female adolescents' psychological health: a randomised controlled trial in South Africa Prof Tonya Renee Thurman,

Volume 388, Issue 10058, Pages (November 2016)

Volume 393, Issue 10172, Pages (February 2019)

Fully closed-loop insulin delivery improves glucose control of inpatients with type 2 diabetes receiving hemodialysis Lia Bally, Philipp Gubler, Hood.

Tuberculosis case detection by trained inmate peer educators in a resource-limited prison setting in Ethiopia: a cluster-randomised trial Kelemework.

Community groups or mobile phone messaging to prevent and control type 2 diabetes and intermediate hyperglycaemia in Bangladesh (DMagic): a cluster-randomised.

Muh Geot Wong, Vlado Perkovic The Lancet Diabetes & Endocrinology

Thank you to our diverse (but not diverse enough) reviewers

Volume 4, Issue 5, Pages (May 2017)

Volume 6, Issue 3, Pages (March 2019)

Matthieu J Guitton The Lancet Planetary Health

Spatial lifecourse epidemiology

Effect of a behaviour change intervention on the quality of peri-urban sanitation in Lusaka, Zambia: a randomised controlled trial James B Tidwell, PhD,

Impact of renal function on the effects of LDL cholesterol lowering with statin-based regimens: a meta-analysis of individual participant data from 28.

Volume 5, Issue 1, Pages (January 2018)

Effectiveness of strategies to improve health-care provider practices in low-income and middle-income countries: a systematic review Alexander K Rowe,

How concentrated are academic publications of countries' progression towards universal health coverage? Adrian Gheorghe, Kalipso Chalkidou, Anthony Culyer

Robot assisted training for the upper limb after stroke (RATULS): a multicentre randomised controlled trial Prof Helen Rodgers, FRCP, Helen Bosomworth,

Improving management of neonatal infections

The effect of the Alive & Thrive initiative on exclusive breastfeeding in rural Burkina Faso: a repeated cross-sectional cluster randomised controlled.

Refining treatment choices for ADHD

Levels and trends in contraceptive prevalence, unmet need, and demand for family planning for 29 states and union territories in India: a modelling study.

Clinic attendance and disengagement of young adults with type 1 diabetes after transition of care from paediatric to adult services (TrACeD): a randomised,

Median (interquartile range) of sensor glucose (A) and insulin delivery (B) during closed-loop (solid red line and red shaded area) and control period.

Economic decline, incarceration, and mortality from drug use disorders in the USA between 1983 and 2014: an observational analysis Elias Nosrati, PhD,

The dilemma of vaginal breech delivery worldwide

Chat-based instant messaging support integrated with brief interventions for smoking cessation: a community-based, pragmatic, cluster-randomised controlled.

Sickle cell disease: a new era

Presentation transcript:

Closed-loop insulin delivery in inpatients with type 2 diabetes: a randomised, parallel- group trial Hood Thabit, PhD, Sara Hartnell, BSc, Janet M Allen, RN, Andrea Lake, DipHE, Malgorzata E Wilinska, PhD, Yue Ruan, MEng, Mark L Evans, MD, Anthony P Coll, PhD, Dr Roman Hovorka, PhD The Lancet Diabetes & Endocrinology Volume 5, Issue 2, Pages 117-124 (February 2017) DOI: 10.1016/S2213-8587(16)30280-7 Copyright © 2017 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY license Terms and Conditions

Figure 1 Trial profile The Lancet Diabetes & Endocrinology 2017 5, 117-124DOI: (10.1016/S2213-8587(16)30280-7) Copyright © 2017 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY license Terms and Conditions

Figure 2 Median sensor glucose concentration and insulin delivery (A) Median (IQR) sensor glucose concentration during closed-loop insulin delivery (the solid red line and the red shaded area) and control interventions (the dashed black line and the grey shaded area) from 0000 h to 0000 h. The lower and upper limits of the target glucose concentration range of 5·6–10·0 mmol/L are denoted by the horizontal dashed lines. (B) Median (IQR) algorithm-directed insulin delivery during the closed-loop intervention. The Lancet Diabetes & Endocrinology 2017 5, 117-124DOI: (10.1016/S2213-8587(16)30280-7) Copyright © 2017 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY license Terms and Conditions

Figure 3 Participant responses to the questionnaire about closed-loop insulin delivery The Lancet Diabetes & Endocrinology 2017 5, 117-124DOI: (10.1016/S2213-8587(16)30280-7) Copyright © 2017 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY license Terms and Conditions