Therapeutic Agents in Phase II Clinical Trials for Alzheimer’s Disease

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Presentation transcript:

Therapeutic Agents in Phase II Clinical Trials for Alzheimer’s Disease AADvac1 ABBV-8E12 (C2N8E12) Albumin + Immunoglobulin ANAVEX2-73 AstroStem (stem cells) Atomoxetine AZD0530 (Saracatanib) BAC BAN2401 Benfotiamine BI 425809 BIIB092 Boost A (dietary supplement) Brainport (berry extract) Bryostatin 1 CAD106 Candesartan CB-AC-02 (stem cells) CERE-110 Cilostazol CNP520 CPC-201 Crenezumab CT1812 Curcumin DAOIB Deferiprone DHP1401 Elderberry Juice Elenbecestat (E2609) Fesoterodine Formoterol Freshly-pressed extra virgin olive oil Gantenerumab Ginkgo biloba (with or without donepezil) Grape powder Grape Seed Extract GV1001 Human mesenchymal stem cells Human neural stem cells Icosapent ethyl / Omega-3 fatty acid ID1201 Insulin (nasal) Insulin detemir Insulin glulisine IONIS MAPTRx JNJ-54861911 Lanabecestat (LY3314814, AZD3293) Levetiracetam Liraglutide (Victoza®) Lithium LM11A-31-BHS Losartan, Amlodipine & Atorvastatin combination therapy L-serine LY3002813 LY3202626 MB2 (TRx0237, methylene Blue) MLC901 Montelukast buccal film Neflamapimod NeuroStem (stem cells) Nicotinamide Nicotine Nilotinib Octagam Omega-3 fatty acid ORM-12741 Oxybutynin Perindopril Pirometaline Polyamine dietary supplement Pomegranate Juice Posiphen® Probucol Rasagiline Riluzole RO7105705 Rotigotine transdermal patch add-on to AChEI therapy S47445 Sargramostim (Leukine®) S-Equol Simvastatin (Zocor®) Simvastatin + L-Arginine + Tetrahydrobiopterin (SLAT) STA-1 (plus donepezil) SUVN-502 T3D-959 Thiethylperazine UB 311 UCMSC (stem cells) Valaciclovir Xanamem For related symptoms: AXS-05 (agitation) Bupropion (agitation) Cannabis oil (agitation) Lemborexant (sleep) MP-101 (psychosis) Nabilone/ Dronabinol (agitation) Pimavanserin (agitation, psychosis) As of 04/2018