Portrait of a Stem Cell Developmental Cell Caroline Erter Burns, Leonard I. Zon  Developmental Cell  Volume 3, Issue 5, Pages 612-613 (November 2002) DOI: 10.1016/S1534-5807(02)00329-5

Figure 1 Cartoon Depicting Stem Cell Asymmetric Division Theoretically, all stem cells, represented here by ESC, HSC, and NSC, may share a core set of “stemness” genes that enable both self-renewal and differentiation. These internal programs may be regulated by environmental cues. Each individual SC also expresses a set of individual lineage-specific genes. The specific combination of common and lineage-specific transcripts and the biased distribution of internal factors may lead to SC asymmetric division. Developmental Cell 2002 3, 612-613DOI: (10.1016/S1534-5807(02)00329-5)