Letting Go of JuNK by Disassembly of Adhesive Complexes

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Presentation transcript:

Letting Go of JuNK by Disassembly of Adhesive Complexes Jonathan E. Farley, Marc R. Freeman Neuron Volume 88, Issue 5, Pages 848-850 (December 2015) DOI: 10.1016/j.neuron.2015.11.015 Copyright © 2015 Elsevier Inc. Terms and Conditions

Figure 1 JNK-FasII Signaling in Drosophila MBɣ Neuron Pruning (A) MBɣ neurons remodeling in the Drosophila brain during the larval and pupal stages. bsk mutant clones (green) fail to prune axons, but not dendrites, while control clones (gray) prune both compartments normally. (B) Bsk negatively regulates surface expression of FasII in control cells (gray), but FasII levels and adhesion are increased in bsk mutant cells (green). (C) Genetic pathways of developmental pruning in Drosophila MBɣ neurons (see text for details). Neuron 2015 88, 848-850DOI: (10.1016/j.neuron.2015.11.015) Copyright © 2015 Elsevier Inc. Terms and Conditions