Helene Bry-Gauillard, M. D. , Geri Meduri, M. D. , Ph. D

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Primary amenorrhea revealing an occult progesterone-secreting ovarian tumor Helene Bry-Gauillard, M.D., Geri Meduri, M.D., Ph.D., Fadi Abirached, M.D., Elisabeth Constancis, M.D., Sylvie Brailly, M.D., Philippe Chanson, M.D., Jacques Young, M.D., Ph.D. Fertility and Sterility Volume 90, Issue 4, Pages 1198.e1-1198.e5 (October 2008) DOI: 10.1016/j.fertnstert.2007.11.064 Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions

Figure 1 Location and pathologic examination of the tumor. (A) Plasma progesterone (P) and testosterone (T) levels in the ovarian veins and in a peripheral vein. The data are the mean (±SD) of two samples taken at 15-min intervals. (B) 1: Pelvic sonography showing a solid mass in the hilus region of the right ovary; 2: macroscopic aspect of the tumor; 3: microscopic aspect of the tumor; 4–6: tumor expression of P450 scc (4) and 3β-HSD (5) and very low expression of P450c17 (6). Fertility and Sterility 2008 90, 1198.e1-1198.e5DOI: (10.1016/j.fertnstert.2007.11.064) Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions