Volume 5, Issue 1, Pages (January 2018)

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Volume 5, Issue 1, Pages 31-40 (January 2018) AVATAR therapy for auditory verbal hallucinations in people with psychosis: a single- blind, randomised controlled trial Prof Tom KJ Craig, PhD, Mar Rus-Calafell, PhD, Thomas Ward, DClinPsy, Prof Julian P Leff, FRCPsych, Prof Mark Huckvale, PhD, Elizabeth Howarth, PhD, Prof Richard Emsley, PhD, Prof Philippa A Garety, PhD The Lancet Psychiatry Volume 5, Issue 1, Pages 31-40 (January 2018) DOI: 10.1016/S2215-0366(17)30427-3 Copyright © 2017 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license Terms and Conditions

Figure 1 Trial profile Numbers lost to follow-up are cumulative in relation to the total allocated at the start of the study. The Lancet Psychiatry 2018 5, 31-40DOI: (10.1016/S2215-0366(17)30427-3) Copyright © 2017 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license Terms and Conditions

Figure 2 Week 12 effect estimates and 95% CIs Forest plot shows standardised Cohen's d effect sizes for AVATAR versus supportive counselling. Positive effect favours AVATAR therapy. All scales reversed, except for VAAS and MANSA. PSYRATS-AH= Psychotic Symptoms Rating Scales–Auditory Hallucinations. BAVQ-R=Beliefs About Voices Questionnaire. VAAS=Voice Acceptance and Action Scale. VPDS=Voice Power Differential Scale. DASS-21=Depression Anxiety and Stress Scale. PSYRATS–DEL=Psychotic Symptoms Rating Scales–Delusions. SAPS=Scale for Assessment of Positive Symptoms. SANS=Scale for Assessment of Negative Symptoms. MANSA=Manchester Quality of Life. MAP=Maudsley Addiction Profile. The Lancet Psychiatry 2018 5, 31-40DOI: (10.1016/S2215-0366(17)30427-3) Copyright © 2017 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license Terms and Conditions

Figure 3 PSYRATS–AH total, distress, and frequency scores The Lancet Psychiatry 2018 5, 31-40DOI: (10.1016/S2215-0366(17)30427-3) Copyright © 2017 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license Terms and Conditions