KIR2DS4 and Its Variant KIR1D Are Associated with Acute Graft-versus-Host Disease, Cytomegalovirus, and Overall Survival after Sibling-Related HLA-Matched.

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Presentation transcript:

KIR2DS4 and Its Variant KIR1D Are Associated with Acute Graft-versus-Host Disease, Cytomegalovirus, and Overall Survival after Sibling-Related HLA-Matched Transplantation in Patients with Donors with KIR Gene Haplotype A Xiaojin Wu, Yao Yao, Xiaojing Bao, Huifeng Zhou, Xiaowen Tang, Yue Han, Xiao Ma, Yuejun Liu, Jia Chen, Haixia Zhou, Song Jing, Bing Gu, Yang Xu, Aining Sun, Jun He, Depei Wu Biology of Blood and Marrow Transplantation Volume 22, Issue 2, Pages 220-225 (February 2016) DOI: 10.1016/j.bbmt.2015.10.004 Copyright © 2016 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 1 Recovery of neutrophils (A) and platelets (B) for the whole cohort. Biology of Blood and Marrow Transplantation 2016 22, 220-225DOI: (10.1016/j.bbmt.2015.10.004) Copyright © 2016 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 2 Cumulative incidences of grade II-IV aGVHD (A) and grade III-IV aGVHD (B). Biology of Blood and Marrow Transplantation 2016 22, 220-225DOI: (10.1016/j.bbmt.2015.10.004) Copyright © 2016 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 3 Cumulative incidences of cGVHD. Biology of Blood and Marrow Transplantation 2016 22, 220-225DOI: (10.1016/j.bbmt.2015.10.004) Copyright © 2016 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 4 Cumulative incidences of relapse. Biology of Blood and Marrow Transplantation 2016 22, 220-225DOI: (10.1016/j.bbmt.2015.10.004) Copyright © 2016 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 5 Cumulative incidences of TRM. Biology of Blood and Marrow Transplantation 2016 22, 220-225DOI: (10.1016/j.bbmt.2015.10.004) Copyright © 2016 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 6 Estimated rate of CMV reactivation. Biology of Blood and Marrow Transplantation 2016 22, 220-225DOI: (10.1016/j.bbmt.2015.10.004) Copyright © 2016 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 7 Estimated 3-year probability of OS in first year (A) and beyond 1 year (B). Biology of Blood and Marrow Transplantation 2016 22, 220-225DOI: (10.1016/j.bbmt.2015.10.004) Copyright © 2016 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 8 Estimated 3-year probability of DFS in advanced-stage patients. Biology of Blood and Marrow Transplantation 2016 22, 220-225DOI: (10.1016/j.bbmt.2015.10.004) Copyright © 2016 American Society for Blood and Marrow Transplantation Terms and Conditions