Ampullary Pyloric Gland Adenoma with High-grade Dysplasia (Video)

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Ampullary Pyloric Gland Adenoma with High-grade Dysplasia (Video) Shou-jiang Tang, Ruonan Wu, William P. Daley  Video Journal and Encyclopedia of GI Endoscopy  Volume 2, Issue 3, Pages 90-94 (December 2014) DOI: 10.1016/j.vjgien.2015.03.001 Copyright © 2015 The Authors Terms and Conditions

Figure 1 Endoscopic views of the ampullary pyloric gland adenoma under white light endoscopy (A) and under digital chromoendoscopy (B). The PGA displays a smooth mucosal surface with minimal pit patterns, unlike those pit patterns observed in tubular and villous adenomas. Video Journal and Encyclopedia of GI Endoscopy 2014 2, 90-94DOI: (10.1016/j.vjgien.2015.03.001) Copyright © 2015 The Authors Terms and Conditions

Figure 2 Endoscopic duodenal mucosa around the minor ampulla under white light endoscopy. Biopsy showed duodenal mucosa with gastric mucin-cell metaplasia and reactive epithelial changes, consistent with peptic duodenitis. Video Journal and Encyclopedia of GI Endoscopy 2014 2, 90-94DOI: (10.1016/j.vjgien.2015.03.001) Copyright © 2015 The Authors Terms and Conditions

Figure 3 Endoscopic views of the ampullary adenoma after submucosal injection (A), post-ampullectomy base with an ERCP wire guide inside the pancreatic duct (B), a placed PD stent and an endoclip closed the distal margins of the ampullectomy base (C). Video Journal and Encyclopedia of GI Endoscopy 2014 2, 90-94DOI: (10.1016/j.vjgien.2015.03.001) Copyright © 2015 The Authors Terms and Conditions

Figure 4 Histopathological images of the resected pyloric gland adenoma: prismatic columnar epithelium showing basal nuclei and pale eosinophilic cytoplasm and forming some ectatic foveolae (H&E ×40) (A), pyloric gland adenoma with round basal nuclei (H&E ×200) (B) and (H&E ×200) (C), antibodies against Mucin 6 stain in deep gastric glands (×200) (D). Video Journal and Encyclopedia of GI Endoscopy 2014 2, 90-94DOI: (10.1016/j.vjgien.2015.03.001) Copyright © 2015 The Authors Terms and Conditions