Volume 119, Issue 3, Pages (September 2000)

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Presentation transcript:

Volume 119, Issue 3, Pages 677-682 (September 2000) Endoscopic detection of dysplasia in patients with Barrett's esophagus using light- scattering spectroscopy Michael B. Wallace, Lev T. Perelman, Vadim Backman, James M. Crawford, Marianne Fitzmaurice, Maurice Seiler, Kamran Badizadegan, Steven J. Shields, Irving Itzkan, Ramachandra R. Dasari, Jacques Van Dam, Michael S. Feld Gastroenterology Volume 119, Issue 3, Pages 677-682 (September 2000) DOI: 10.1053/gast.2000.16511 Copyright © 2000 American Gastroenterological Association Terms and Conditions

Fig. 1 Schematic diagram of the LSS system. Gastroenterology 2000 119, 677-682DOI: (10.1053/gast.2000.16511) Copyright © 2000 American Gastroenterological Association Terms and Conditions

Fig. 2 Percentage of enlarged (≥10 μm) nuclei and nuclear surface density (number of nuclei per 100 μm2), as determined by LSS, for each of the 76 biopsy sites of the study set. The average histologic diagnoses are indicated: NDB (circles), IND (squares), LGD (triangles), and HGD (diamonds). Filled symbols denote samples diagnosed as dysplasia. Shaded symbols denote the 8 samples of the modeling set. Dashed line indicates the dysplasia/nondysplasia threshold used in the prospective evaluation. Gastroenterology 2000 119, 677-682DOI: (10.1053/gast.2000.16511) Copyright © 2000 American Gastroenterological Association Terms and Conditions