Was ADH1B under Selection in European Populations?

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Was ADH1B under Selection in European Populations? Quan-Kuan Shen, Xierzhatijiang Sulaiman, Yong-Gang Yao, Min-Sheng Peng, Ya-Ping Zhang The American Journal of Human Genetics Volume 99, Issue 5, Pages 1217-1219 (November 2016) DOI: 10.1016/j.ajhg.2016.09.017 Copyright © 2016 American Society of Human Genetics Terms and Conditions

Figure 1 Signals of Selection in the Top Four PCs of European Populations from the 1000 Genomes Project The vertical axis is the Di2 statistic following a chi-square (with 1 df) distribution on the basis of the PCA result. For most large Di2 values, it is impossible to calculate the exact corresponding p values (in most cases, p = 0), so we adopted the top values to show the results. The black dashed line indicates the top 0.1% threshold. The American Journal of Human Genetics 2016 99, 1217-1219DOI: (10.1016/j.ajhg.2016.09.017) Copyright © 2016 American Society of Human Genetics Terms and Conditions

Figure 2 PCA Results on European Populations from the 1000 Genomes Project We preformed quality control, a Hardy-Weinberg equilibrium test, and linkage-disequilibrium filtering as described in Galinsky et al.1 by using PLINK 1.9.8 After that, a total of 1,063,058 SNPs were analyzed in FastPCA. The American Journal of Human Genetics 2016 99, 1217-1219DOI: (10.1016/j.ajhg.2016.09.017) Copyright © 2016 American Society of Human Genetics Terms and Conditions