Ahmad Nofal, MD, Rania Alakad, MSc, Magda Assaf, PhD, Eman Nofal, MD

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Presentation transcript:

A fatal case of febrile ulceronecrotic Mucha-Habermann disease in a child Ahmad Nofal, MD, Rania Alakad, MSc, Magda Assaf, PhD, Eman Nofal, MD JAAD Case Reports Volume 2, Issue 2, Pages 181-185 (March 2016) DOI: 10.1016/j.jdcr.2016.03.002 Copyright © 2016 American Academy of Dermatology, Inc. Terms and Conditions

Fig 1 Febrile ulceronecrotic Mucha-Habermann disease. Generalized ulceronecrotic papules and plaques covering the whole trunk. JAAD Case Reports 2016 2, 181-185DOI: (10.1016/j.jdcr.2016.03.002) Copyright © 2016 American Academy of Dermatology, Inc. Terms and Conditions

Fig 2 Flexural accentuation of the ulceronecrotic lesions on the neck. JAAD Case Reports 2016 2, 181-185DOI: (10.1016/j.jdcr.2016.03.002) Copyright © 2016 American Academy of Dermatology, Inc. Terms and Conditions

Fig 3 Mucosal erosions on the tongue and lips. JAAD Case Reports 2016 2, 181-185DOI: (10.1016/j.jdcr.2016.03.002) Copyright © 2016 American Academy of Dermatology, Inc. Terms and Conditions

Fig 4 A, Histopathologic examination of a necrotic plaque shows full-thickness epidermal necrosis, prominent lymphocytic infiltrate, and focal hemorrhage. B, Histopathologic examination of a nonnecrotic lesion shows keratinocytes necrosis, exocytosis, and vacuolar interface dermatitis. (A and B, Hematoxylin-eosin stain; original magnifications: A, ×100; B, ×400.) JAAD Case Reports 2016 2, 181-185DOI: (10.1016/j.jdcr.2016.03.002) Copyright © 2016 American Academy of Dermatology, Inc. Terms and Conditions

Fig 5 Severe confluent ulceronecrotic plaques covering most of the total body surface area. JAAD Case Reports 2016 2, 181-185DOI: (10.1016/j.jdcr.2016.03.002) Copyright © 2016 American Academy of Dermatology, Inc. Terms and Conditions

Fig 6 Multiple ecthyma gangrenosum lesions associated with Pseudomonas septicemia. JAAD Case Reports 2016 2, 181-185DOI: (10.1016/j.jdcr.2016.03.002) Copyright © 2016 American Academy of Dermatology, Inc. Terms and Conditions