Volume 63, Issue 1, Pages 3-4 (July 2016)

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Volume 63, Issue 1, Pages 3-4 (July 2016) Persister Awakening Kim Lewis, Yue Shan Molecular Cell Volume 63, Issue 1, Pages 3-4 (July 2016) DOI: 10.1016/j.molcel.2016.06.025 Copyright © 2016 Elsevier Inc. Terms and Conditions

Figure 1 A Novel Molecular Mechanism of Samonella Persister Formation and Resuscitation Samonella toxin TacT acetylates aminoacyl-tRNA to inhibit translation. The action of the toxin may explain the increase in persisters in Samonella upon entry into macrophages. The hydrolase Pth cleaves off the acetylated aminoacyl-releasing free tRNA, translation resumes, and persisters wake up. Molecular Cell 2016 63, 3-4DOI: (10.1016/j.molcel.2016.06.025) Copyright © 2016 Elsevier Inc. Terms and Conditions