Eun-Jung Jung, George A. Calin Cancer Cell

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The Meaning of 21 in the MicroRNA World: Perfection Rather than Destruction? Eun-Jung Jung, George A. Calin Cancer Cell Volume 18, Issue 3, Pages 203-205 (September 2010) DOI: 10.1016/j.ccr.2010.08.015 Copyright © 2010 Elsevier Inc. Terms and Conditions

Figure 1 The Molecular Mechanism Involving miR-21 and the Clinical Significance of miR-21 Overexpression in Lung Cancers The left panel represents the complex mechanism reported by Hatley and colleagues (“the perfection” of miR-21 function), whereas the right panel indicates the main clinical applications (that transform miR-21 “destructive” potential to a clinically useful potential). The gene names are as provided in the NCBI database at http://www.ncbi.nlm.nih.gov/gene. Cancer Cell 2010 18, 203-205DOI: (10.1016/j.ccr.2010.08.015) Copyright © 2010 Elsevier Inc. Terms and Conditions