Guidelines on genetic evaluation and management of Lynch syndrome: A consensus statement by the U.S. Multi-Society Task Force on Colorectal Cancer  Francis M. Giardiello, John I. Allen, Jennifer E. Axilbund, C. Richard Boland, Carol A. Burke, Randall W. Burt, James M. Church, Jason A. Dominitz, David A. Johnson, Tonya Kaltenbach, Theodore R. Levin, David A. Lieberman, Douglas J. Robertson, Sapna Syngal, Douglas K. Rex  Gastrointestinal Endoscopy  Volume 80, Issue 2, Pages 197-220 (August 2014) DOI: 10.1016/j.gie.2014.06.006 Copyright © 2014 American Society for Gastrointestinal Endoscopy, American Gastroenterological Association, American College of Gastroenterology, and the American Society of Colon and Rectal Surgeons. Terms and Conditions

Figure 1 Colorectal cancer risk assessment tool. Adapted with permission from Kastrinos et al.101 Gastrointestinal Endoscopy 2014 80, 197-220DOI: (10.1016/j.gie.2014.06.006) Copyright © 2014 American Society for Gastrointestinal Endoscopy, American Gastroenterological Association, American College of Gastroenterology, and the American Society of Colon and Rectal Surgeons. Terms and Conditions

Figure 2 Universal screening by tumor testing. Gastrointestinal Endoscopy 2014 80, 197-220DOI: (10.1016/j.gie.2014.06.006) Copyright © 2014 American Society for Gastrointestinal Endoscopy, American Gastroenterological Association, American College of Gastroenterology, and the American Society of Colon and Rectal Surgeons. Terms and Conditions

Figure 3 Traditional testing strategy indications and genetic counseling. Gastrointestinal Endoscopy 2014 80, 197-220DOI: (10.1016/j.gie.2014.06.006) Copyright © 2014 American Society for Gastrointestinal Endoscopy, American Gastroenterological Association, American College of Gastroenterology, and the American Society of Colon and Rectal Surgeons. Terms and Conditions

Figure 4 Traditional testing strategy when family mutation known. Gastrointestinal Endoscopy 2014 80, 197-220DOI: (10.1016/j.gie.2014.06.006) Copyright © 2014 American Society for Gastrointestinal Endoscopy, American Gastroenterological Association, American College of Gastroenterology, and the American Society of Colon and Rectal Surgeons. Terms and Conditions

Figure 5 Traditional testing strategy when patient is clinically affected and the family mutation is unknown. Gastrointestinal Endoscopy 2014 80, 197-220DOI: (10.1016/j.gie.2014.06.006) Copyright © 2014 American Society for Gastrointestinal Endoscopy, American Gastroenterological Association, American College of Gastroenterology, and the American Society of Colon and Rectal Surgeons. Terms and Conditions

Figure 6 Traditional testing strategy of at-risk family member when family mutation is unknown. Gastrointestinal Endoscopy 2014 80, 197-220DOI: (10.1016/j.gie.2014.06.006) Copyright © 2014 American Society for Gastrointestinal Endoscopy, American Gastroenterological Association, American College of Gastroenterology, and the American Society of Colon and Rectal Surgeons. Terms and Conditions