Modelling a risk classification of aneuploidy in human embryos using non-invasive morphokinetics  Alison Campbell, Simon Fishel, Natalie Bowman, Samantha.

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Modelling a risk classification of aneuploidy in human embryos using non-invasive morphokinetics  Alison Campbell, Simon Fishel, Natalie Bowman, Samantha Duffy, Mark Sedler, Cristina Fontes Lindemann Hickman  Reproductive BioMedicine Online  Volume 26, Issue 5, Pages 477-485 (May 2013) DOI: 10.1016/j.rbmo.2013.02.006 Copyright © 2013 Reproductive Healthcare Ltd. Terms and Conditions

Figure 1 Time-lapse images of the same embryo demonstrating its appearance at specific time points as utilized in this study. (A) Human embryo at 106.8hpi, with the start of a cavity forming (arrow), at tSB. (B) Human blastocyst at 112.1hpi, with a blastocoele filling the embryo with <10% increase in its diameter, at tB. Reproductive BioMedicine Online 2013 26, 477-485DOI: (10.1016/j.rbmo.2013.02.006) Copyright © 2013 Reproductive Healthcare Ltd. Terms and Conditions

Figure 2 The three classes of aneuploidy risk (low, medium and high) based on time from insemination to a full blastocoele where the blastocyst has not yet started expansion (tB) and time from insemination to start of blastulation (tSB). Area under the receiver operating characteristic curve is 0.72.hpi=hours post insemination. Reproductive BioMedicine Online 2013 26, 477-485DOI: (10.1016/j.rbmo.2013.02.006) Copyright © 2013 Reproductive Healthcare Ltd. Terms and Conditions

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