Kenshi Hayashi et al. JACEP 2016;2:279-287 Distribution of Study Patients and the Frequency of LQTS Mutation Carriers by the 1993, 2006, and 2011 Criteria The application of the 2011 criteria significantly increased the number of patients identified with a high probability of long QT syndrome (LQTS). The probability of carrying mutations in patients with a high probability of LQTS was comparable among the 3 criteria. *p = 0.0002 or †p = 0.0014 versus high probability using the 2011 criteria; ‡p = 0.0014 or §p = 0.0013 versus mutation carriers with intermediate probability using the 2011 criteria. High = high probability of having LQTS; Intermediate = intermediate probability of having LQTS; Low = low probability of having LQTS. Kenshi Hayashi et al. JACEP 2016;2:279-287 American College of Cardiology Foundation