S. Biswas, D. Raoult, J.-M. Rolain Clinical Microbiology and Infection

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Presentation transcript:

Molecular characterisation of resistance to rifampin in Bartonella quintana S. Biswas, D. Raoult, J.-M. Rolain Clinical Microbiology and Infection Volume 15, Pages 100-101 (December 2009) DOI: 10.1111/j.1469-0691.2008.02179.x Copyright © 2009 European Society of Clinical Infectious Diseases Terms and Conditions

Fig. 1 Kinetic of decrease of the diameter of growth inhibition around the disk of rifampin during the selection of the mutant strain of B. quintana Oklahoma cultured on blood agar plates (a), and amino acid (AA) sequences (E. coli numbering) of Rifampin-susceptible (RifS) and rifampin-resistant (RifR) strains of B. Quintana showing the Ser531Phe mutation (b). Structure of RNA polymerase showing the ß subunit, the binding site of the antibiotic rifampin (c). Clinical Microbiology and Infection 2009 15, 100-101DOI: (10.1111/j.1469-0691.2008.02179.x) Copyright © 2009 European Society of Clinical Infectious Diseases Terms and Conditions