N. Samuel, A.H. Taub, R. Paz, A. Raz British Journal of Anaesthesia

Slides:

Advertisements

Similar presentations

Pavlovian Conditioning, Fear Circuits and Extinction of Fear Valance Wang Translational Neuromodeling & Computational Neuroeconomics Fall 2013.

Advertisements

Discriminative Auditory Fear Learning Requires Both Tuned and Nontuned Auditory Pathways to the Amygdala Raquel Antunes and Marta A. Moita Champalimaud.

Fear Conditioning Michael Davis’ Ponca Symposium Presentation (notes from)

The Amygdala and Emotional Memory The amygdala is a complicated collection of nuclei found in the medial portion of the temporal lobe. It is a phylogenetically.

2015 Alzheimer's disease facts and figures Alzheimer's & Dementia: The Journal of the Alzheimer's Association Volume 11, Issue 3, Pages (March.

Ventral Medial Prefrontal Cortex and Emotional Perseveration: The Memory for Prior Extinction Training Maria A. Morgan, Jay Schulkin, Joseph E. LeDoux.

Prior cocaine exposure disrupts extinction of fear conditioning

Building Better Models of Visual Cortical Receptive Fields

مهارتهای آموزشی و پرورشی ( روشها و فنون تدریس) تالیف: دکتر حسن شعبانی.

The Amygdala and Fear Conditioning: Has the Nut Been Cracked?

Volume 75, Issue 1, Pages (July 2012)

Emotional memory: What does the amygdala do?

Elizabeth A. Phelps, Joseph E. LeDoux Neuron

Human factors in anaesthesia: lessons from aviation

Alexander W. Johnson Trends in Neurosciences

Disambiguating pharmacological mechanisms from placebo in neuropathic pain using functional neuroimaging V. Wanigasekera, K. Wartolowska, J.P. Huggins,

Presynaptic inhibition of the release of multiple major central nervous system neurotransmitter types by the inhaled anaesthetic isoflurane R.I. Westphalen,

Propofol compared with sevoflurane general anaesthesia is associated with decreased delayed neurocognitive recovery in older adults Y. Zhang, G.-J. Shan,

Dyspnoea: underlying mechanisms and treatment

Christiane M Thiel, Karl J Friston, Raymond J Dolan Neuron

Fear conditioning, synaptic plasticity and the amygdala: implications for posttraumatic stress disorder Amy L. Mahan, Kerry J. Ressler Trends in Neurosciences

Posterior parietal cortex

L. Pain, A. Launoy, N. Fouquet, P. Oberling

Aryeh Hai Taub, Rita Perets, Eilat Kahana, Rony Paz Neuron

Barriers to clinical research in Africa: a quantitative and qualitative survey of clinical researchers in 27 African countries A. Conradie, R. Duys,

Rachel Yehuda, Joseph LeDoux Neuron

Effect of propofol on the medial temporal lobe emotional memory system: a functional magnetic resonance imaging study in human subjects K.O. Pryor, J.C.

Gating of Fear in Prelimbic Cortex by Hippocampal and Amygdala Inputs

Pain after orthopaedic surgery: differences in patient reported outcomes in the United States vs internationally. An observational study from the PAIN.

Complete heart block during central venous catheter placement in a patient with pre- existing left bundle branch block D Unnikrishnan, N Idris, N Varshneya

Volume 81, Issue 2, Pages (January 2014)

Neuromuscular junction in health and disease

Schrödinger's cat: anaesthetised and not!

Pituitary disease and anaesthesia

Volume 3, Issue 3, Pages (September 2008)

Psychology of pain British Journal of Anaesthesia

Expertise in practice: an ethnographic study exploring acquisition and use of knowledge in anaesthesia A. Smith, D. Goodwin, M. Mort, C. Pope British.

M.C. Alvarado, K.L. Murphy, M.G. Baxter British Journal of Anaesthesia

Volume 17, Issue 20, Pages R868-R874 (October 2007)

Christian Büchel, Jond Morris, Raymond J Dolan, Karl J Friston Neuron

Volume 23, Issue 6, Pages (March 2013)

Amygdala Inhibitory Circuits and the Control of Fear Memory

Synapse-Specific Encoding of Fear Memory in the Amygdala

Patricio T Huerta, Linus D Sun, Matthew A Wilson, Susumu Tonegawa

Marco Pignatelli, Antonello Bonci Neuron

Synaptic Plasticity, Engrams, and Network Oscillations in Amygdala Circuits for Storage and Retrieval of Emotional Memories Marco Bocchio, Sadegh Nabavi,

Interaction between the Amygdala and the Medial Temporal Lobe Memory System Predicts Better Memory for Emotional Events Florin Dolcos, Kevin S LaBar,

Volume 20, Issue 5, Pages (May 1998)

FastrachTM tubes: modifying the design for use with the LMA CTrachTM?

Ki A Goosens, Jennifer A Hobin, Stephen Maren Neuron

Uvula necrosis after fibreoptic intubation

Volume 83, Issue 4, Pages (August 2014)

Incidence, characteristics, and predictive factors for medication errors in paediatric anaesthesia: a prospective incident monitoring study C. Gariel,

A unique effect of propofol on the jaw opening reflex

The association between obesity and disability in survivors of joint surgery: analysis of the health and retirement study T.G. Gaulton, L.A. Fleisher,

III. Animal behaviour testing: memory

Disinhibition, a Circuit Mechanism for Associative Learning and Memory

Volume 70, Issue 5, Pages (June 2011)

Teamwork, communication, and anaesthetic assistance in Scotland

J Lee, S Gupta, C Price, A.P. Baranowski

Fig. 3. Mice which experienced MS or MSEW did not exhibit impairments in hippocampal and amygdala-dependent fear-related emotional memories. In the acquisition.

ICU fire evacuation preparedness in London: a cross-sectional study

Systematic review of the QoR-15 score, a patient- reported outcome measure measuring quality of recovery after surgery and anaesthesia J. Kleif, J. Waage,

Xenon improves long-term cognitive function, reduces neuronal loss and chronic neuroinflammation, and improves survival after traumatic brain injury in.

Learning Learning is a relatively permanent change in behavior that occurs as a result of experience. Associative Learning- learning to associate 2 events,

Unconscious learning during surgery with propofol anaesthesia†

Volume 84, Issue 2, Pages (October 2014)

Michael S. Avidan, John P.A. Ioannidis, George A. Mashour

Classical Conditioning

Volume 75, Issue 1, Pages (July 2012)

Presentation transcript:

Implicit aversive memory under anaesthesia in animal models: a narrative review N. Samuel, A.H. Taub, R. Paz, A. Raz British Journal of Anaesthesia Volume 121, Issue 1, Pages 219-232 (July 2018) DOI: 10.1016/j.bja.2018.05.046 Copyright © 2018 British Journal of Anaesthesia Terms and Conditions

Fig 1 Pavlovian aversive conditioning using a tone-conditioned stimulus (CS) and foot shock-unconditioned stimulus (US). (a) Example of common apparatuses and paradigm for fear conditioning (FeC) in rodents. In the example, the tone-CS is delivered through a loudspeaker and is presented ahead of a short electrical shock delivered to the limbs of the mouse through the metal grid (left). The unconditioned response (UR) is freezing in response to the unconditioned stimulus (US) and the conditioned response (CR) is freezing in response to the CS. During acquisition, the CS and US are repeatedly presented together (middle) and the paired CS–US conditioning results in increase freezing time in response to the CS (right). (b) During extinction, the animal is located in the same environment as during acquisition (left) but the CS is presented alone (middle), a manipulation that results in decreased CR (right). British Journal of Anaesthesia 2018 121, 219-232DOI: (10.1016/j.bja.2018.05.046) Copyright © 2018 British Journal of Anaesthesia Terms and Conditions

Fig 2 Neuronal substrates of tone-shock conditioning. The tone-conditioned stimulus (CS) and somatosensory-unconditioned stimulus (US) are delivered through the thalamus to the auditory and somatosensory cortices, respectively, and to the basolateral amygdala (BLA). The CS and US reach the amygdala via the cortices and CS–US association is formed in the BLA. After conditioning, CS presentation results in the BLA to central amygdala (CeA) activation and the CeA delivers the neuronal conditioned response (CR) to downstream structures responsible for generating behavioural, autonomic, and endocrine responses. On the right side of the figure is an anatomic presentation of the relevant structures in a brain slice from a rat (top) and MRI of a rhesus monkey (bottom). Amy, amygdala; Ctx, cortex; Hipp, hippocampus; mPFC, medial prefrontal cortex; Thal, thalamus. British Journal of Anaesthesia 2018 121, 219-232DOI: (10.1016/j.bja.2018.05.046) Copyright © 2018 British Journal of Anaesthesia Terms and Conditions