Working heart model of heterotopic heart-lung transplantation in rats

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Presentation transcript:

Working heart model of heterotopic heart-lung transplantation in rats Toshiyuki Maruyama, MD, Marc T. Swartz, Lawrence R. McBride, MD, D.Glenn Pennington, MD The Journal of Thoracic and Cardiovascular Surgery Volume 107, Issue 1, Pages 210-215 (January 1994) DOI: 10.5555/uri:pii:S0022522394704724 Copyright © 1994 Mosby, Inc. Terms and Conditions

Fig. 1 Schema of the model: Heterotopic, abdominally positioned heart-lung graft with donor ascending aorta and left pulmonary artery anastomosed to recipient abdominal aorta. Abd. aorta, Recipient's abdominal aorta; IVC, inferior vena cava; LA, left atrium; LV, left ventricle; RA, right atrium; RV, right ventricle; CS, coronary sinus. The Journal of Thoracic and Cardiovascular Surgery 1994 107, 210-215DOI: (10.5555/uri:pii:S0022522394704724) Copyright © 1994 Mosby, Inc. Terms and Conditions

Fig. 2 Representative tracing of hemodynamic recordings. Aortic pressure tracing (AoP) shows ejection from both donor and recipient left ventricles. LVP, Donor left ventricular pressure; dP/dt, first derivative of the donor left ventricular presure; LAP, donor left atrial pressure; Flow, donor ascending aortic flow; Vol, ejected volume by the donor left ventricle (integration of the ejected flow). The Journal of Thoracic and Cardiovascular Surgery 1994 107, 210-215DOI: (10.5555/uri:pii:S0022522394704724) Copyright © 1994 Mosby, Inc. Terms and Conditions

Fig. 3 Correlation between stroke volume and left ventricular weight. SV, Stroke volume; LVW, left ventricular weight. The Journal of Thoracic and Cardiovascular Surgery 1994 107, 210-215DOI: (10.5555/uri:pii:S0022522394704724) Copyright © 1994 Mosby, Inc. Terms and Conditions