Risk of stroke early after implantation of a left ventricular assist device Takaaki Samura, MD, Daisuke Yoshioka, MD, PhD, Koichi Toda, MD, PhD, Ryoto.

Slides:

Advertisements

Similar presentations

A wolf in sheep's clothing

Advertisements

Is individualized mitral valve repair in the future?

Anemia Is a Risk Factor of New Intraoperative Hemorrhagic Stroke During Valve Surgery for Endocarditis Daisuke Yoshioka, MD, Koichi Toda, MD, PhD, Shuhei.

Risk Index for Postoperative Acute Kidney Injury After Valvular Surgery Using Cardiopulmonary Bypass Takashi Yamauchi, MD, PhD, Shigeru Miyagawa, MD,

Visualization of vortex flow and shear stress in the aortic root during left ventricular assist device support Shohei Yoshida, MD, Satsuki Fukushima,

A hybrid configuration of a left ventricular assist device and venovenous extracorporeal membrane oxygenation Louis Samuels, MD, Eric Gnall, DO, Elena.

Minimally invasive left ventricular assist device implantation with outflow graft anastomosis to the innominate artery Jasmin S. Hanke, MD, Sebastian.

Increased cyclic guanosine monophosphate levels and continuous-flow left-ventricular assist devices: Implications for gastrointestinal bleeding Liza.

Impact of Early Surgical Treatment on Postoperative Neurologic Outcome for Active Infective Endocarditis Complicated by Cerebral Infarction Daisuke Yoshioka,

The American Association for Thoracic Surgery 2016 Ethics Forum: Cost-effectiveness and the ethics of left ventricular assist device therapy John W.C.

Shinichi Fukuhara, MD, Koji Takeda, MD, PhD, Paul A

The RECOVER I: A multicenter prospective study of Impella 5

Libman-Sacks Endocarditis Due to Systemic Lupus Erythematosus Activation After Mitral Valve Plasty Takaaki Samura, MD, Koichi Toda, MD, PhD, Daisuke.

Stenting of an outflow graft obstruction after implantation of a continuous-flow, axial-flow left ventricular assist device Duc Thinh Pham, MD, Navin.

Association of device surface and biomaterials with immunologic sensitization after mechanical support Isaac George, MD, Patrick Colley, BS, Mark J.

Long-term biventricular support with rotary blood pumps in a patient with a noncontractile heart Taichi Sakaguchi, MD, Shunsuke Saito, MD, Daisuke Yoshioka,

The days of future past Neel K. Ranganath, MD, Aubrey C. Galloway, MD

Midventricular Obstruction Caused by Abnormal Intra–Left Ventricular Septum and Papillary Muscles Takaaki Samura, MD, Koichi Toda, MD, PhD, Shunsuke.

Effects on pre- and posttransplant pulmonary hemodynamics in patients with continuous-flow left ventricular assist devices Ranjit John, MD, Kenneth Liao,

Intrinsic cardiac stem cells are essential for regeneration

Elucidating the intricate mechanisms of gastrointestinal bleeding in a continuous-flow left ventricular assist device will lead to future therapeutic.

Form ever follows function

Victor van Berkel, MD, PhD

Go on-pump or off-pump in diabetic patients?

New treatment approaches create new disease processes: A short guide on how to reduce unexpected events to a minimum Martin Czerny, MD, MBA The Journal.

Resuscitation practices in cardiac surgery

Right ventricular failure in patients with the HeartMate II continuous-flow left ventricular assist device: Incidence, risk factors, and effect on outcomes

Intra-aortic balloon pump therapy negatively affects flow through a continuous-flow left ventricular assist device Dipanjan Banerjee, MD, MS, Chun Choi,

Risk-corrected impact of mechanical versus bioprosthetic valves on long-term mortality after aortic valve replacement Ole Lund, MD, PhD, Martin Bland,

The lord of the rings Antonio Miceli, MD, PhD

Outcomes after implantation of partial-support left ventricular assist devices in inotropic- dependent patients: Do we still need full-support assist devices?

Is individualized mitral valve repair in the future?

A technique for implanting outflow cannulas for Berlin Heart EXCOR ventricular assist device in small pediatric patients Khanh Nguyen, MD The Journal.

Reduced pleural drainage, length of stay, and readmissions using a modified Fontan management protocol Nancy A. Pike, PhD, Carol A. Okuhara, MN, Joy.

Expanding left ventricular assist device use to patients with disabilities: The role of assistive technology Juan A. Crestanello, MD The Journal of.

Intra-aortic balloon pumps and continuous flow left ventricular assist devices: Don't let balloon pumps overstay their welcome Kevin G. Soucy, PhD, Steven.

Long-term outcome of patients on continuous-flow left ventricular assist device support Koji Takeda, MD, PhD, Hiroo Takayama, MD, PhD, Bindu Kalesan,

Adverse events in contemporary continuous-flow left ventricular assist devices: A multi- institutional comparison shows significant differences John M.

Left ventricular assist device therapy in a patient with hearing and speech disabilities Sotirios Spiliopoulos, MD, PhD, Vera Hergesell, MD, Otto Dapunt,

Abdul Rahman Dakkak, MD, Angelo M. Dell'Aquila, MD, Juergen R

A first start for lung transplantation?

Right ventricular failure after cardiac surgery: Why can't right ventricular assist device support fix the problem? Francis D. Pagani, MD, PhD The Journal.

Joshua M. Rosenblum, MD, PhD, Bradley G. Leshnower, MD, Rena C

Successful combined procedure of HeartMate II left ventricular assist device implantation and minimally invasive transapical aortic valve replacement

William L. Holman, MD, James K. Kirklin, MD, David C

Minimally invasive off-pump implantation of HeartMate 3 left ventricular assist device Diyar Saeed, MD, PhD, Stephan Sixt, MD, PhD, Alexander Albert,

Chronic obstructive pulmonary disease severity influences outcomes after off-pump coronary artery bypass Benjamin Medalion, MD, Michael G. Katz, MD,

Niv Ad, MD, Lawrence M. Wei, MD

Anticoagulation with apixaban in a patient with a left ventricular assist device and gastrointestinal bleeding: A viable alternative to warfarin? Francesco.

The Ross procedure: Time to reevaluate the guidelines

Manuel J. Antunes, MD, PhD, DSc

Video-assisted resection for lung cancer results in fewer complications Lunxu Liu, PhD, MD, FRCS The Journal of Thoracic and Cardiovascular Surgery

Passing the torch The Journal of Thoracic and Cardiovascular Surgery

Sutureless valve implantation: Every detail counts

Left ventricular assist device implantation after acute anterior wall myocardial infarction and cardiogenic shock: A two-center study Nicholas C. Dang,

The impact of frailty on postoperative delirium in cardiac surgery patients Patrick Jung, BSc, Michael Ashley Pereira, BSc, Brett Hiebert, MSc, Xiaiwei.

The Journal of Thoracic and Cardiovascular Surgery

Discussion The Journal of Thoracic and Cardiovascular Surgery

The future of cardiac surgery training: A survival guide

Ventricular assistant in restrictive cardiomyopathy: Making the right connection Robert D.B. Jaquiss, MD The Journal of Thoracic and Cardiovascular Surgery

Cerebrovascular accidents in patients with a ventricular assist device

Seeing is believing: A call for routine early postoperative hemodynamic transesophageal echocardiography monitoring after left ventricular assist device.

“The more things change…”: The challenges ahead

Optimal timing for heart transplantation in patients bridged with left ventricular assist devices: Is timing of the essence? Chase R. Brown, MD, Fabliha.

Why arch curvature affects arch resistance

Energized lung resections

Daisuke Yoshioka, MD, Hiroo Takayama, MD, Arthur R. Garan, MD, Veli K

Gastrointestinal bleeding after left ventricular assist device implantation: It is all about the platelets Juan A. Crestanello, MD The Journal of Thoracic.

Did you like Terminator 3 better than Terminator 2

Lessons learned from Melody valve retrieved at transplantation

Presentation transcript:

Risk of stroke early after implantation of a left ventricular assist device Takaaki Samura, MD, Daisuke Yoshioka, MD, PhD, Koichi Toda, MD, PhD, Ryoto Sakaniwa, MD, Mikito Shimizu, MD, Shigeru Miyagawa, MD, PhD, Yasushi Yoshikawa, MD, PhD, Hiroki Hata, MD, PhD, Shunsuke Saito, MD, PhD, Yasushi Sakata, MD, PhD, Yoshiki Sawa, MD, PhD The Journal of Thoracic and Cardiovascular Surgery Volume 157, Issue 1, Pages 259-267.e1 (January 2019) DOI: 10.1016/j.jtcvs.2018.06.031 Copyright © 2018 The American Association for Thoracic Surgery Terms and Conditions

Figure 1 A, Incidence rates of overall stroke in the entire cohort. B, Hazard function of stroke after LVAD implantation. LVAD, Left ventricular assist device. The Journal of Thoracic and Cardiovascular Surgery 2019 157, 259-267.e1DOI: (10.1016/j.jtcvs.2018.06.031) Copyright © 2018 The American Association for Thoracic Surgery Terms and Conditions

Figure 2 Postoperative course of (A) INR, (B) aPTT, and (C) serum LDH levels during the first postoperative 2 weeks. The horizontal line in the middle of each box indicates the median; the top and bottom borders of the box mark the 75th and 25th percentiles, respectively; and the whiskers mark the 90th and 10th percentiles. INR, International normalized ratio; CVA, cerebrovascular accident; LVAD, left ventricular assist device; aPTT, activated partial thromboplastin time; LDH, lactate dehydrogenase. The Journal of Thoracic and Cardiovascular Surgery 2019 157, 259-267.e1DOI: (10.1016/j.jtcvs.2018.06.031) Copyright © 2018 The American Association for Thoracic Surgery Terms and Conditions

Figure 3 Postoperative course of (A) the minimum cardiac output in patients with stroke (red line) versus stroke-free patients (blue line) and (B) minimum cardiac index in patients with stroke (red line) versus stroke-free patients (blue line) after LVAD implantation. CVA, Cerebrovascular accident; LVAD, left ventricular assist device. The Journal of Thoracic and Cardiovascular Surgery 2019 157, 259-267.e1DOI: (10.1016/j.jtcvs.2018.06.031) Copyright © 2018 The American Association for Thoracic Surgery Terms and Conditions

Figure 4 Postoperative course of (A) the minimum cardiac output in patients with stroke (red line) versus stroke-free patients (blue line) after axial type LVAD implantation and (B) the minimum cardiac output in patients with stroke (red line) versus stroke-free patients (blue line) after centrifugal type LVAD implantation. CVA, Cerebrovascular accident; LVAD, left ventricular assist device. The Journal of Thoracic and Cardiovascular Surgery 2019 157, 259-267.e1DOI: (10.1016/j.jtcvs.2018.06.031) Copyright © 2018 The American Association for Thoracic Surgery Terms and Conditions

Figure 5 The relationship between the minimum cardiac output and the LDH (A) at 3 days, (B) 7 days, and (C) 2 weeks after implantation of the HeartMate II (Abbott Medical, Abbott Park, Ill). LDH, Lactate dehydrogenase. The Journal of Thoracic and Cardiovascular Surgery 2019 157, 259-267.e1DOI: (10.1016/j.jtcvs.2018.06.031) Copyright © 2018 The American Association for Thoracic Surgery Terms and Conditions

Postoperative course of the minimum cardiac output in patients with stroke versus stroke-free patients. The Journal of Thoracic and Cardiovascular Surgery 2019 157, 259-267.e1DOI: (10.1016/j.jtcvs.2018.06.031) Copyright © 2018 The American Association for Thoracic Surgery Terms and Conditions

Video 1 The video briefly summarizes the important findings of this study. Video available at: https://www.jtcvs.org/article/S0022-5223(18)31765-3/fulltext. The Journal of Thoracic and Cardiovascular Surgery 2019 157, 259-267.e1DOI: (10.1016/j.jtcvs.2018.06.031) Copyright © 2018 The American Association for Thoracic Surgery Terms and Conditions