Focus Lesson We are working on the DIAGRAM column. Your diagram should be meaningful and purposeful. That means don’t draw a BLOB. THINK. BE SPECIFIC. This is your review.

Daily Objective List and evaluate the use of biotechnology. Analyze requirements and benefits in order to make decisions about the use of technology (not monetarily). Explain how biotechnology can impact health.

How will we get there? Last Class This Class FCIM: Example Column Notes: Mutations (Page 15) Mutation examples Point Frameshift Duplication Translocation Home Learning Check your work on Page 14 Study Vocabulary FCIM: Diagram Column CSI DNA Crime Scene Transcription/ Translation Phenotypic Expression Notes: Biotechnology DNA Fingerprinting Genetic engineering cloning Genetically modified crops Gene sequencing Gene therapy

We will read the handout as a class. Explore Page 16: CSI Lab We will read the handout as a class. The front of the handout is basically a key that you will use to determine the phenotypic expression of the DNA. You will follow the directions and complete the assignment individually, using your table group ONLY if you get stuck.

Analyzing Our Results Do all of our drawings look the same? Would we be able to make an arrest without a shred of a doubt? Do you think this is how police ACTUALLY use DNA found at the crimescene?

Notes: What is Biotechnology? Page 17 What does the prefix bio mean? Life or living What is technology? the practical application of knowledge especially in a particular area In your own words: What do you think biotechnology means?

Uses of biotechnology DNA finger printing Genetic engineering cloning Genetically modified crops Gene sequencing Gene therapy

DNA Finger Printing DNA technology is used in courts of law DNA Finger Printing DNA technology is used in courts of law DNA fingerprinting can help solve crimes Figure 12.12B Defendant’s blood Blood from defendant’s clothes Victim’s

Group white board practice

Genetic engineering The changing of an organism’s DNA to give the organism new traits Rhesus Monkey Retro Question: What characteristic of DNA allows scientists to put the DNA of a firefly into the DNA of a monkey?

Scientists can engineer a monkey to glow, because it’s cool… Scientists can engineer a monkey to glow, because it’s cool… But what other reasons might they have to genetically modify organisms? Can you think of a way to modify plants/crops to help farmers? What kind of plant structures might they want to alter?

Genetically Modified Organisms (GMOs) Examples: Putting genes from artic fish into tomatoes. Fish have codons that translate into cold resistance proteins. This can create a frost resistant crop! Putting genes from soil bacteria into corn. Some soil bacteria produce a protein which kills crop eating pests. This creates a pest resistant crop!

Cloning A genetically identical copy of a gene or organism Retro Question: What process creates a gamete? In a sheep, where does this process occur?

Gene Sequencing Determining the order of nucleotides in genes or the entire genome. Retro question: In the karyotype to the right do you see a chromosomal or a gene mutation?

Gene therapy The replacement of a defective or missing gene Retro Question: What is that newly inserted viral DNA going to create ? (What is a function of DNA?)

Review Exit Slip: Check your knowledge Explain why a frameshift mutation would have a greater effect than a point mutation. 2. Would you utilize biotechnology? What if you were able to DESIGN your baby to have all of the traits you like? Is that okay to do? WHY OR WHY NOT?