Hormones of the Pituitary Gland

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Hormones of the Pituitary Gland 01/01/2019 Dr. Omary Chillo (MD, PhD)

Dr. Omary Chillo (MD, PhD) 01/01/2019 Dr. Omary Chillo (MD, PhD)

Dr. Omary Chillo (MD, PhD) Hypothalamus Neuronal cells Neuro hypophysis Epitheloid cells Posterior Pituitary Adeno hypophysis Anterior Pituitary Pars intermedia 01/01/2019 Dr. Omary Chillo (MD, PhD)

The Anterior Pituitary cells and Hormones Acidophils Somatotropes GH ACTH TSH FSH LH PRL Corticotropes Thyrotropes Gonadotropes lactotropes 01/01/2019 Dr. Omary Chillo (MD, PhD)

The Posterior Pituitary cells and Hormones Paraventricular neurones Supraoptic neurones Magnocellular Neurone Posterior Pituitary Oxytocin ADH 01/01/2019 Dr. Omary Chillo (MD, PhD)

Hypothalamus controls pituitary secretions Releasing or Inhibiting Hormones Nerve Signals 01/01/2019 Dr. Omary Chillo (MD, PhD)

Hypothalamic-Hypophysial Portal System 01/01/2019 Dr. Omary Chillo (MD, PhD)

Hypothalamus Releasing/Inhibitory Hormones Thyrotropin-releasing H (TRH) TSH Corticotropin-releasing H (CRH) ACTH GH-releasing H (GHRH) GH GH-inhibiting H (Somatostatin) GH Gonadotropin-releasing H (GnRH) FSH LH Prolactin-inhibitory H (PIH) PRL 01/01/2019 Dr. Omary Chillo (MD, PhD) Clip

Dr. Omary Chillo (MD, PhD) Which kind of hormones from the anterior pituitary will be released following a removal of hypothalamus? 01/01/2019 Dr. Omary Chillo (MD, PhD)

Anterior Pituitary Hormones TSH CRH Anterior Pituitary FSH, LH Prolactin Growth Hormone 01/01/2019 Dr. Omary Chillo (MD, PhD)

The Growth Hormone Actions of Growth Hormone: increase in cell size (hypertrophy) increase in number of cells (hyperplasia) Actions of Growth Hormone: - increases skeletal growth - increases muscular growth - increases amino acid uptake and protein synthesis - increased use of lipids for energy - decreased glucose uptake in tissues (diabetogenic) 01/01/2019 Dr. Omary Chillo (MD, PhD)

Protein Deposition in Tissues 01/01/2019 Dr. Omary Chillo (MD, PhD)

Dr. Omary Chillo (MD, PhD) 01/01/2019 Dr. Omary Chillo (MD, PhD)

Dr. Omary Chillo (MD, PhD) 01/01/2019 Dr. Omary Chillo (MD, PhD)

Dr. Omary Chillo (MD, PhD) 01/01/2019 Dr. Omary Chillo (MD, PhD)

Regulation of GH release GHRH somatostatin Gs Gi (-) cAMP PKA PIT-1 GH synthesis GH levels are low during the day, but increase during sleep. There is an overall increase in GH levels during puberty. 01/01/2019 Dr. Omary Chillo (MD, PhD)

Abnormalities of Growth Hormone Due to lack of GH release from the pituitary, or lack of GH receptor expression________ Excessive secretion of growth hormone________ and ________ ? Growth Hormone effect on Aging 01/01/2019 Dr. Omary Chillo (MD, PhD)

The Posterior Pituitary cells and Hormones Paraventricular neurones Supraoptic neurones Magnocellular Neurone Posterior Pituitary Oxytocin ADH 01/01/2019 Dr. Omary Chillo (MD, PhD)

Dr. Omary Chillo (MD, PhD) Thanks 01/01/2019 Dr. Omary Chillo (MD, PhD)